Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in Panama City on Hotels.com. These Panama City hotels consistently deliver on comfort, location and traveler experience. Last updated on .
Hotels in Panama City
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Hotel Riu Plaza Panama
Hotel Riu Plaza PanamaBella Vista
9.0 out of 10, Wonderful, (5,610 reviews)
$147 nightly
The price is $162
Jun 29 - Jun 30
Total with taxes and fees

Plaza Paitilla Inn Hotel
Plaza Paitilla Inn HotelSan Francisco
9.4 out of 10, Exceptional, (2,170 reviews)
$97 nightly
The price is $107
Jul 16 - Jul 17
Total with taxes and fees

JW Marriott Panama
JW Marriott PanamaSan Francisco
9.0 out of 10, Wonderful, (1,000 reviews)
$255 nightly
The price is $281
Jul 11 - Jul 12
Total with taxes and fees

Principe Hotel and Suites
Principe Hotel and SuitesBella Vista
9.0 out of 10, Wonderful, (1,894 reviews)
$57 nightly
The price is $62
Jun 27 - Jun 28
Total with taxes and fees

Ramada Plaza by Wyndham Panama Punta Pacifica
Ramada Plaza by Wyndham Panama Punta PacificaSan Francisco
9.6 out of 10, Exceptional, (1,241 reviews)
$101 nightly
The price is $111
Jun 27 - Jun 28
Total with taxes and fees

Decapolis Hotel Panama City
Decapolis Hotel Panama CitySan Francisco
8.6 out of 10, Excellent, (1,690 reviews)
$96 nightly
The price is $106
Jun 23 - Jun 24
Total with taxes and fees

Sheraton Grand Panama
Sheraton Grand PanamaSan Francisco
8.6 out of 10, Excellent, (1,002 reviews)
$132 nightly
The price is $145
Jul 4 - Jul 5
Total with taxes and fees

Novotel Panama City
Novotel Panama CityBella Vista
9.2 out of 10, Wonderful, (1,211 reviews)
$108 nightly
The price is $119
Jun 28 - Jun 29
Total with taxes and fees

The Executive Hotel
The Executive HotelBella Vista
9.2 out of 10, Wonderful, (1,155 reviews)
$89 nightly
The price is $98
Jul 21 - Jul 22
Total with taxes and fees

Las Americas Golden Tower Panama
Las Americas Golden Tower PanamaSan Francisco
9.0 out of 10, Wonderful, (1,041 reviews)
$132 nightly
The price is $145
Jun 29 - Jun 30
Total with taxes and fees

Riande Urban Hotel
Riande Urban HotelBella Vista
8.8 out of 10, Excellent, (1,036 reviews)
$87 nightly
The price is $96
Jul 12 - Jul 13
Total with taxes and fees

Marriott Panama Hotel
Marriott Panama HotelPanama City
9.0 out of 10, Wonderful, (1,001 reviews)
$161 nightly
The price is $177
Jun 28 - Jun 29
Total with taxes and fees

Waymore Hotel Spa & Casino
Waymore Hotel Spa & CasinoBella Vista
9.0 out of 10, Wonderful, (971 reviews)
$109 nightly
The price is $120
Jun 21 - Jun 22
Total with taxes and fees

Courtyard by Marriott Panama Multiplaza Mall
Courtyard by Marriott Panama Multiplaza MallSan Francisco
9.0 out of 10, Wonderful, (1,001 reviews)
$114 nightly
The price is $125
Jul 4 - Jul 5
Total with taxes and fees

Hilton Panama
Hilton PanamaBella Vista
9.0 out of 10, Wonderful, (1,001 reviews)
$253 nightly
The price is $278
Jun 27 - Jun 28
Total with taxes and fees

Megapolis Hotel Panamá
Megapolis Hotel PanamáSan Francisco
8.4 out of 10, Very Good, (1,567 reviews)
$131 nightly
The price is $145
Jul 19 - Jul 20
Total with taxes and fees

TRYP by Wyndham Panamá Centro
TRYP by Wyndham Panamá CentroBella Vista
9.0 out of 10, Wonderful, (1,002 reviews)
$80 nightly
The price is $88
Jun 21 - Jun 22
Total with taxes and fees

Hyatt Regency Panama City
Hyatt Regency Panama CityBella Vista
9.6 out of 10, Exceptional, (345 reviews)
$211 nightly
The price is $232
Jun 26 - Jun 27
Total with taxes and fees

Bristol Panama, a Registry Collection Hotel
Bristol Panama, a Registry Collection HotelBella Vista
9.4 out of 10, Exceptional, (1,000 reviews)
$225 nightly
The price is $247
Jul 17 - Jul 18
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Showing deals for:Jun 26 - Jun 28

8.4 out of 10, Very Good, (1,567 reviews)
$430 off
$133 nightly
The price is $294
Total with taxes and fees
Showing deals for:Jul 20 - Jul 21

9.4 out of 10, Exceptional, (402 reviews)
$21 off
$153 nightly
The price is $168
Total with taxes and fees
Check out hotels with a pool in Panama City

8.6 out of 10, Excellent, (2594)
$141 nightly
The price is $155
Jul 19 - Jul 20
Total with taxes and fees
You may also like family-friendly hotels in Panama City

8.6 out of 10, Excellent, (2594)
$141 nightly
The price is $155
Jul 19 - Jul 20
Total with taxes and fees
You can also stay at pet-friendly hotels in Panama City

8.4 out of 10, Very Good, (1812)
$111 nightly
The price is $123
Jul 16 - Jul 17
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Go beyond your typical stay in Panama City
Apart hotel
Top neighborhoods in Panama City

Casco Viejo
Casco Viejo's cobblestone streets tell Panama's colonial story at every turn. The golden Metropolitan Cathedral and historic theaters create a living museum vibe. Rooftop bars offer spectacular bay views while museums showcase Panama's diverse heritage. Plaza hopping rewards you with hidden architectural gems and cultural performances that bring history to life. The neighborhood serves up everything from fusion cuisine in restored mansions to traditional Panamanian dishes. Boutique hotels occupy colonial buildings with charming courtyards and personalized service. Though compact, comfortable walking shoes are essential for navigating the uneven historic streets.

Photo by My World
Open Photo by My World
Bella Vista
Bella Vista balances Panama City's sleek business side with upscale urban living. Gleaming skyscrapers along Avenida Balboa house financial headquarters while trendy spots on Calle Uruguay buzz with after-work crowds. Shop at MultiPlaza Pacific mall, visit Crown Casino, or simply stroll the waterfront promenade for stunning bay views. Getting around is a breeze with two metro stations and plentiful taxis. Dining options range from rooftop restaurants to international cuisine that won't disappoint. High-rise hotels with spectacular views cater to business travelers and tourists who appreciate modern comforts with a side of ocean breeze.

El Cangrejo
El Cangrejo pulses with modern energy around the iconic "El Tornillo" tower, where art meets business in Panama City's cosmopolitan heart. Korean BBQ aromas mingle with coffee scents from sidewalk cafes, while galleries showcase local talent beneath tropical sunshine. Colorful murals splash across office buildings as diverse cultures blend in this trendy district. The neighborhood serves up an eclectic fusion of Korean, Jewish, and Panamanian cuisines in stylish eateries and casual cafes. Modern boutique hotels and upscale business lodging dominate accommodation options. Getting around is a breeze with nearby Metro Line 1 stations, abundant taxis, and pleasantly walkable streets.

Obarrio
Obarrio dazzles with gleaming skyscrapers housing Panama City's financial powerhouses and luxury shopping. Multiplaza Pacific mall tempts with designer boutiques while the business crowd buzzes between meetings. When you're not trying your luck at local casinos, relax at a sophisticated coffeehouse or stroll the wide, clean sidewalks of Calle 50. Hotels range from international chains to boutique properties, with rates reflecting the upscale surroundings. Getting around is a breeze with excellent taxi service, frequent buses along Via España, and the Metro Line 1 connecting directly to Iglesia del Carmen station.

Punta Pacifica
Punta Pacifica's gleaming glass towers and an iconic sail-shaped skyscraper create a skyline that screams luxury with a Pacific Ocean backdrop. Stroll the waterfront promenades where swaying palms frame perfect sunset views, or duck into Multiplaza Pacific Mall to browse designer boutiques in marble-floored splendor. The neighborhood balances business and pleasure with its mix of corporate offices and upscale leisure spots. Dining here means international cuisine with ocean views at rooftop bars and hotel restaurants where reservations are smart moves. High-rise hotels and serviced apartments offer amenities like infinity pools and concierge services. Getting around is easy with abundant taxis and walkable streets, though you won't find much public transit in this polished enclave.
Top landmarks in Panama City
Learn more about Panama City
Wander through the historic Casco Viejo district, marveling at colorful colonial buildings and bustling plazas. Cruise through the famous Panama Canal, watching massive ships navigate the ingenious locks system.

Check out reviews of Panama City hotels guests love

Hotel Riu Plaza Panama
8/10 Good
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