Hotels in Panama City

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Where to stay in Panama City?

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Great weekend hotel deals in Panama City

Showing deals for:25 July - 27 July

Top neighbourhoods in Panama City

Casco Viejo map

Casco Viejo

Panama City's Casco Viejo neighbourhood is known for its bars and offers lots of things to see, such as Metropolitan Cathedral of Panama and Interoceanic Canal Museum.

Bella Vista map

Bella Vista

Panama City's Bella Vista neighbourhood is known for its cafes and restaurants, and entices visitors with attractions, including Via Espana and Iglesia del Carmen.

El Cangrejo map

El Cangrejo

Panama City's El Cangrejo neighbourhood is known for its restaurants and cafes, and entices visitors with attractions, including Crown Casino and Luxor Towers.

San Francisco map

San Francisco

Panama City's San Francisco neighbourhood is known for its restaurants and offers lots of things to see, such as ATLAPA Conventions Center and Multiplaza Pacific Mall.

Punta Paitilla map

Punta Paitilla

Panama City's Punta Paitilla neighbourhood is known for its restaurants and live music, and entices visitors with attractions, including Avenida Balboa and Multicentro Panama.

Top landmarks in Panama City

Learn more about Panama City

Panama City is hailed for its casinos and skyscrapers, while top attractions include Albrook Shopping Mall. Visitors speak highly of this city's cafes and scenic setting with sights including Via Espana and Iglesia del Carmen.

Check out reviews of Panama City hotels guests love

Frequently asked questions

Can I book a refundable accommodation option in Panama City?
If you want the flexibility to change your plans to Panama City, most hotels offer refundable* rates that you can book. You can see this accommodation by searching our site and using the "fully refundable" filter to narrow the results down.
Where can I stay in Panama City if I want a holiday rental instead of a hotel?
If you're looking for a good alternative to a hotel, browse our selection of 53 holiday homes. In addition, there are 817 apartments and 53 condos.
What will the weather in Panama City be like during my visit?
With an average temperature of 26°C during the coldest months, Panama City is a great place to visit at any time of year.
Why should I book my Panama City hotel with Hotels.com?
There are plenty of reasons to book your Panama City travel with us: our free cancellations on selected hotels* gives you the flexibility you're looking for, our Price Guarantee ensures that you always get the lowest price, and you can earn rewards on every booking.