Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in Murphysboro on Hotels.com. These Murphysboro hotels consistently deliver on quality, location and traveler experience. Last updated on .
Hotels in Murphysboro

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1. Walker's Bluff Casino Resort
Walker's Bluff Casino ResortCarterville
9.4 out of 10, Exceptional, (544 reviews)
$120 nightly
The price is $133
Nov 30 - Dec 1
Total with taxes and fees

2. Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
Holiday Inn Express & Suites Murphysboro - Carbondale by IHGMurphysboro
9.4 out of 10, Exceptional, (630 reviews)
$97 nightly
The price is $108
Dec 14 - Dec 15
Total with taxes and fees

3. Holiday Inn Express & Suites Carbondale - University Area by IHG
Holiday Inn Express & Suites Carbondale - University Area by IHGCarbondale
8.8 out of 10, Excellent, (763 reviews)
$101 nightly
The price is $116
Nov 22 - Nov 23
Total with taxes and fees

4. Drury Inn & Suites Marion
Drury Inn & Suites MarionMarion
9.4 out of 10, Exceptional, (1,002 reviews)
$94 nightly
The price is $113
Nov 29 - Nov 30
Total with taxes and fees

5. Home2 Suites by Hilton Carbondale
Home2 Suites by Hilton CarbondaleCarbondale
8.8 out of 10, Excellent, (600 reviews)
$128 nightly
The price is $147
Nov 25 - Nov 26
Total with taxes and fees

6. Super 8 by Wyndham Carbondale
Super 8 by Wyndham CarbondaleCarbondale
7.4 out of 10, Good, (1,001 reviews)
$60 nightly
The price is $69
Nov 30 - Dec 1
Total with taxes and fees

7. Best Western Saluki Inn
Best Western Saluki InnCarbondale
7.8 out of 10, Good, (1,001 reviews)
$82 nightly
The price is $94
Nov 16 - Nov 17
Total with taxes and fees

8. Hampton Inn Carbondale
Hampton Inn CarbondaleCarbondale
8.2 out of 10, Very good, (710 reviews)
$94 nightly
The price is $108
Nov 23 - Nov 24
Total with taxes and fees

9. Baymont by Wyndham Marion
Baymont by Wyndham MarionMarion
8.4 out of 10, Very good, (1,065 reviews)
$90 nightly
The price is $108
Nov 29 - Nov 30
Total with taxes and fees

10. Comfort Inn & Suites Carbondale University Area
Comfort Inn & Suites Carbondale University AreaCarbondale
7.6 out of 10, Good, (623 reviews)
$76 nightly
The price is $87
Dec 3 - Dec 4
Total with taxes and fees

11. Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MOJackson
9.6 out of 10, Exceptional, (1,001 reviews)
$80 nightly
The price is $85
Nov 22 - Nov 23
Total with taxes and fees

12. Best Western Marion Hotel
Best Western Marion HotelMarion
8.4 out of 10, Very good, (1,000 reviews)
$87 nightly
The price is $104
Nov 22 - Nov 23
Total with taxes and fees

13. Comfort Inn & Suites Marion I-57
Comfort Inn & Suites Marion I-57Marion
9.4 out of 10, Exceptional, (1,002 reviews)
$105 nightly
The price is $126
Nov 22 - Nov 23
Total with taxes and fees

14. Quality Inn Carbondale University area
Quality Inn Carbondale University areaCarbondale
5.8 out of 10, (890 reviews)
$57 nightly
The price is $65
Dec 13 - Dec 14
Total with taxes and fees

15. Country Inn & Suites by Radisson, Marion, IL
Country Inn & Suites by Radisson, Marion, ILMarion
8.6 out of 10, Excellent, (1,001 reviews)
$109 nightly
The price is $130
Nov 22 - Nov 23
Total with taxes and fees

16. Fairgrounds Inn
Fairgrounds InnDu Quoin
7.6 out of 10, Good, (451 reviews)
$76 nightly
The price is $84
Nov 15 - Nov 16
Total with taxes and fees

17. Makanda Inn
Makanda InnMakanda
10.0 out of 10, Exceptional, (41 reviews)
$270 nightly
The price is $299
Nov 15 - Nov 16
Total with taxes and fees

18. Quality Inn & Suites Marion
Quality Inn & Suites MarionMarion
7.0 out of 10, Good, (1,001 reviews)
$65 nightly
The price is $78
Nov 27 - Nov 28
Total with taxes and fees

19. Motel 6 Marion, IL
Motel 6 Marion, ILMarion
7.2 out of 10, Good, (726 reviews)
$65 nightly
The price is $72
Nov 16 - Nov 17
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Go beyond your typical stay in Murphysboro
Pet friendly
Top landmarks in Murphysboro
Learn more about Murphysboro
Barbecue enthusiasts make pilgrimages to 17th Street Barbecue, where smoke-infused ribs have earned national acclaim in this unassuming river town. The General John A. Logan Museum honors the Civil War hero who gave us Memorial Day. Lake Murphysboro State Park offers fishing and hiking trails where bald eagles sometimes soar overhead. Locals cool off at Campground Beach before enjoying downtown's vibrant craft beer scene. The surrounding Shawnee National Forest beckons with dramatic sandstone formations and hidden waterfalls. Don't miss the annual Apple Festival, when the town square transforms into a celebration of all things apple-related, complete with a grand parade that hasn't changed much since 1952.

Check out reviews of Murphysboro hotels guests love

Country Inn & Suites by Radisson, Marion, IL
8/10 Good
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