Hotels in Melrose

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Where to stay in Melrose?

Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in Melrose on Hotels.com. These Melrose hotels consistently deliver on quality, location and traveler experience. Last updated on .

1. Country Inn & Suites by Radisson, Gainesville, FL

Country Inn & Suites by Radisson, Gainesville, FL
3.0 star property
Gainesville
9.2 out of 10, Wonderful, (2,034 reviews)
$88 nightly
The price is $99
Nov 22 - Nov 23
Total with taxes and fees
Country Inn & Suites by Radisson, Gainesville, FL

2. Drury Inn & Suites Gainesville

Drury Inn & Suites Gainesville
3.0 star property
Gainesville
9.6 out of 10, Exceptional, (1,681 reviews)
Feel the Gainesville vibe at this modern hotel with an outdoor pool and hot tub, just minutes from UF and Shands. Free breakfast, WiFi, and parking make your stay effortless, while comfortable beds ensure a restful night.
$105 nightly
The price is $118
Nov 26 - Nov 27
Total with taxes and fees
Drury Inn & Suites Gainesville

3. Sleep Inn & Suites University/Shands

Sleep Inn & Suites University/Shands
2.5 star property
Gainesville
8.8 out of 10, Excellent, (1,332 reviews)
Dive into comfort at this Gainesville spot just minutes from University of Florida and Shands Hospital. The outdoor pool offers a refreshing escape after exploring nearby Ben Hill Griffin Stadium. Free breakfast, WiFi and parking add exceptional value.
$81 nightly
The price is $91
Dec 4 - Dec 5
Total with taxes and fees
Sleep Inn & Suites University/Shands

4. Hotel Indigo Gainesville-Celebration Pointe by IHG

Hotel Indigo Gainesville-Celebration Pointe by IHG
3.5 star property
Gainesville
9.2 out of 10, Wonderful, (1,062 reviews)
Set in Celebration Pointe, this hotel offers an inviting outdoor pool and on-site dining options. Just a short drive from UF campus and Ben Hill Griffin Stadium, guests appreciate the helpful staff and convenient location with free WiFi and parking.
$102 nightly
The price is $115
Nov 22 - Nov 23
Total with taxes and fees
Hotel Indigo Gainesville-Celebration Pointe by IHG

5. Hotel Eleo at the University of Florida

Hotel Eleo at the University of Florida
3.0 star property
Gainesville
9.4 out of 10, Exceptional, (1,317 reviews)
$170 nightly
The price is $191
Nov 24 - Nov 25
Total with taxes and fees
Hotel Eleo at the University of Florida

6. Hyatt Place Gainesville Downtown

Hyatt Place Gainesville Downtown
3.0 star property
Downtown Gainesville
9.2 out of 10, Wonderful, (1,251 reviews)
Embrace comfort at this centrally located spot, just a 5-minute drive from University of Florida and Shands. Cool off in the outdoor pool, enjoy American cuisine at The Placery, or grab a quick bite at the snack bar/deli.
$104 nightly
The price is $116
Nov 16 - Nov 17
Total with taxes and fees
Hyatt Place Gainesville Downtown

7. Comfort Suites Gainesville near University

Comfort Suites Gainesville near University
2.5 star property
Gainesville
9.2 out of 10, Wonderful, (1,565 reviews)
Located just minutes from the University of Florida and Shands hospital, this welcoming hotel offers an outdoor pool and 24-hour fitness center. Enjoy free breakfast, WiFi, and parking while staying near Ben Hill Griffin Stadium. Travelers consistently praise the helpful staff.
$83 nightly
The price is $94
Nov 29 - Nov 30
Total with taxes and fees
Comfort Suites Gainesville near University

8. HOM Hotel Gainesville, SureStay Collection by Best Western

HOM Hotel Gainesville, SureStay Collection by Best Western
2.5 star property
Gainesville
8.6 out of 10, Excellent, (2,168 reviews)
$72 nightly
The price is $82
Nov 19 - Nov 20
Total with taxes and fees
HOM Hotel Gainesville, SureStay Collection by Best Western

9. La Quinta by Wyndham Gainesville

La Quinta by Wyndham Gainesville
3.0 star property
Gainesville
9.2 out of 10, Wonderful, (1,389 reviews)
Within a short drive of Ben Hill Griffin Stadium and Oaks Mall, this Gainesville hotel offers free breakfast and parking. After a workout in the fitness center, relax in rooms with comfortable beds. Travelers praise the helpful staff and clean accommodations.
$97 nightly
The price is $109
Nov 15 - Nov 16
Total with taxes and fees
La Quinta by Wyndham Gainesville

10. Best Western Gateway Grand

Best Western Gateway Grand
3.0 star property
Gainesville
8.6 out of 10, Excellent, (1,530 reviews)
Close to Gainesville's major highways, this Tuscan hotel offers a quiet escape with comfortable beds and a beautiful pool. Gator's Den Sports Grill serves American cuisine, while rooms include refrigerators and microwaves for added convenience.
$85 nightly
The price is $95
Nov 19 - Nov 20
Total with taxes and fees
Best Western Gateway Grand

11. Hilton University of Florida Conference Center Gainesville

Hilton University of Florida Conference Center Gainesville
3.5 star property
Gainesville
8.4 out of 10, Very good, (1,000 reviews)
Steps from campus, this hotel offers free WiFi and parking near Ben Hill Griffin Stadium. Cool off in the outdoor pool, work out in the 24-hour fitness center, or enjoy American cuisine at No Name Lounge and the other restaurant.
$106 nightly
The price is $119
Nov 19 - Nov 20
Total with taxes and fees
Hilton University of Florida Conference Center Gainesville

12. DoubleTree by Hilton Gainesville

DoubleTree by Hilton Gainesville
4.0 star property
Gainesville
8.0 out of 10, Very good, (1,000 reviews)
Unwind at this Gainesville hotel with an outdoor pool and garden, just a 10-minute drive from UF and Shands hospital. The fitness center and restaurant offer convenient comforts, while free WiFi and parking enhance your stay.
$84 nightly
The price is $95
Nov 29 - Nov 30
Total with taxes and fees
DoubleTree by Hilton Gainesville

13. Sweetwater Branch Inn

Sweetwater Branch Inn
3.5 star property
Gainesville
9.8 out of 10, Exceptional, (1,000 reviews)
$162 nightly
The price is $182
Dec 2 - Dec 3
Total with taxes and fees
Sweetwater Branch Inn

14. Comfort Inn Gainesville - University Area

Comfort Inn Gainesville - University Area
2.5 star property
Gainesville
8.2 out of 10, Very good, (1,090 reviews)
Just a 10-minute drive from University of Florida and Shands, this hotel offers an outdoor pool and 24-hour fitness center. Guests praise the helpful staff and morning meal. Free WiFi and parking add value near Ben Hill Griffin Stadium.
$85 nightly
The price is $96
Nov 22 - Nov 23
Total with taxes and fees
Comfort Inn Gainesville - University Area

15. Holiday Inn Gainesville - University Center by IHG

Holiday Inn Gainesville - University Center by IHG
3.0 star property
University Heights
8.2 out of 10, Very good, (1,001 reviews)
Located steps from campus, this Gainesville hotel offers Italian dining at Piesanos and an outdoor pool. A quick walk to Ben Hill Griffin Stadium, rooms include microwaves and refrigerators for added convenience.
$97 nightly
The price is $109
Nov 22 - Nov 23
Total with taxes and fees
Holiday Inn Gainesville - University Center by IHG

16. Hampton Inn & Suites Gainesville Downtown University

Hampton Inn & Suites Gainesville Downtown University
3.0 star property
Downtown Gainesville
8.6 out of 10, Excellent, (1,000 reviews)
Just 5 minutes from University of Florida, this downtown hotel offers a refreshing outdoor pool and fitness center. Guests love the helpful staff, free breakfast, and WiFi. Ben Hill Griffin Stadium and Hippodrome State Theatre are located nearby.
$91 nightly
The price is $102
Nov 27 - Nov 28
Total with taxes and fees
Hampton Inn & Suites Gainesville Downtown University

17. Super 8 by Wyndham Gainesville I-75 Hospital University Area

Super 8 by Wyndham Gainesville I-75 Hospital University Area
2.0 star property
Gainesville
7.6 out of 10, Good, (1,065 reviews)
Enjoy the quiet neighborhood and convenient location within a 10-minute drive to UF and Shands Hospital. This hotel offers free WiFi, parking, and breakfast daily from 6-9 AM. Take a refreshing swim in the outdoor pool after exploring nearby attractions.
$50 nightly
The price is $56
Nov 15 - Nov 16
Total with taxes and fees
Super 8 by Wyndham Gainesville I-75 Hospital University Area

18. Gainesville Lodge

Gainesville Lodge
2.0 star property
Gainesville
8.8 out of 10, Excellent, (129 reviews)
Located just minutes from University of Florida and Shands Hospital, this motel offers convenient free parking and WiFi. Nearby Ben Hill Griffin Stadium and Hippodrome State Theatre provide entertainment options while daily housekeeping ensures a comfortable stay.
$71 nightly
The price is $80
Dec 13 - Dec 14
Total with taxes and fees
Gainesville Lodge

19. Red Roof Inn PLUS+ Gainesville

Red Roof Inn PLUS+ Gainesville
2.5 star property
Gainesville
7.4 out of 10, Good, (1,332 reviews)
$58 nightly
The price is $66
Dec 1 - Dec 2
Total with taxes and fees
Red Roof Inn PLUS+ Gainesville

20. Days Inn by Wyndham Gainesville Hospital/University Area

Days Inn by Wyndham Gainesville Hospital/University Area
2.5 star property
Gainesville
7.8 out of 10, Good, (330 reviews)
This tranquil hotel offers a peaceful atmosphere even during busy periods, just a 5-minute drive from University of Florida and Shands Hospital. Ben Hill Griffin Stadium is nearby, and the 24-hour front desk ensures convenience throughout your campus visit.
$51 nightly
The price is $58
Nov 18 - Nov 19
Total with taxes and fees
Days Inn by Wyndham Gainesville Hospital/University Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Melrose

The region around Melrose is home to attractions such as Santa Fe Lake and Waldo Motorsports.

A deer standing behind a wire fence in a wooded area with trees and underbrush.

Check out reviews of Melrose hotels guests love

Frequently asked questions

How much does a hotel room cost in Melrose?
You can choose a great hotel in Melrose from $58 with properties to suit all budgets and needs. If you're after an affordable hotel in Melrose that meets all of your requirements, set your filters and then sort the results by "Price: low to high".
How can I find deals and earn rewards at Melrose hotels?
Discover great deals on Melrose hotel stays with Hotels.com. Take a look at hotel prices mid-week or during the low season as to find those off-peak deals. If you're up for a spontaneous trip, don't forget to check out our last-minute deals on Melrose hotels.
Can I book Melrose hotels with free cancellation?
To book a refundable Melrose hotel on Hotels.com, just filter hotels by "Property cancellation options" and select "Fully refundable property". Most hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.
Can I book a refundable hotel in Melrose?
If you're looking for the flexibility to change your travel plans to Melrose, most accommodations provide refundable* bookable rates. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.
Where can I stay in Melrose if I want a vacation home instead of a traditional hotel?
If you want to find a good alternative to a hotel, browse our selection of 26 vacation homes. You can also book one of the 6 cabins for your stay.
What will the weather in Melrose be like during my trip?
July and August are typically the warmest months in Melrose when the average temp is 80°F. January and February are the coldest months when the average temperature is 60°F. August and July are the months with the most rain.
Why should I book my Melrose accommodation with Hotels.com?
There are lots of reasons to book your Melrose trip with us: our free cancellations on selected hotels gives you flexibility, and with One Keyā„¢, our rewards program, you will be able to earn and use OneKeyCashā„¢* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Find out more about Melrose

Melrose: Where Serene Waters Meet Nature's Embrace

Nestled between the tranquil shores of Lake Santa Fe and the lush landscapes of the nearby Paynes Prairie Preserve State Park, Melrose, Florida, is a hidden gem for nature lovers and adventure seekers. This charming small town offers a serene escape with opportunities for fishing, kayaking, and hiking amidst picturesque scenery. Explore the quaint downtown with its local shops and delightful eateries, or unwind at one of the pristine parks. Just a short drive from Gainesville, Melrose is the perfect off-the-beaten-path retreat, inviting travelers to experience Florida's natural beauty and Southern hospitality.

Discover great hotels near Melrose

Melrose, Florida offers a range of hotel accommodations, from cozy inns to comfortable motels. Whether you’re seeking luxury amenities or budget-friendly options, you'll find various choices to suit your needs. Look out for seasonal deals that make your stay even more enjoyable. Here are some of the most popular hotels with our travelers near Melrose:

  1. Best Western Waldo Inn and SuitesOpens in a new window: This budget-friendly hotel provides a comfortable and inviting atmosphere perfect for leisure travelers seeking a quick getaway. With a guest rating of 8.8 out of 10, it impresses with its clean and cozy accommodations. The property features essential amenities and a pet-friendly policy that ensures a delightful experience for all. Guests appreciate the plentiful breakfast options and the overall cleanliness of the hotel, making it an ideal choice for those looking to unwind after a long journey.
  2. Holiday Inn Express Starke by IHGOpens in a new window: Holiday Inn Express Starke by IHG is a charming budget-friendly hotel that captures the essence of a welcoming escape with a stellar guest rating of 9.6 out of 10. This hotel stands out for its delightful dining options, including a complimentary breakfast that is both warm and satisfying. Visitors rave about the tranquility of their stay, complemented by friendly staff and safe surroundings. Perfect for leisure travelers, Holiday Inn Express Starke by IHG ensures a restful retreat in a cozy atmosphere that enhances the overall experience.
  3. The Laurel Oak Inn Bed and BreakfastOpens in a new window: The Laurel Oak Inn Bed and Breakfast offers a unique Bed and Breakfast experience with a remarkable guest rating of 9.6 out of 10. This hotel is tailored for leisure travelers who appreciate a cozy ambiance combined with complimentary breakfast options. It features inviting accommodations with modern entertainment amenities that promise a relaxing stay. The charm of The Laurel Oak Inn Bed and Breakfast lies in its warm atmosphere and attention to detail, making it a delightful choice for those seeking a distinctive and comfortable stay.

Where to stay near Melrose

When visiting Melrose, Florida, consider staying in Interlachen, Waldo, or Florahome. Interlachen is appealing for its nearby wineries, while Waldo is known for its friendly people and welcoming atmosphere. Florahome offers unique points of interest. For first-time visitors, Waldo is best suited due to its community vibe and accessibility to local attractions.

  1. InterlachenOpens in a new window: Interlachen is a charming town known for its picturesque landscapes and nearby wineries. It's a great place to unwind and enjoy the beauty of nature. You can explore local vineyards, where you can taste various wines and enjoy scenic views. The friendly community vibe makes it a welcoming spot for travelers looking to relax. Plus, with various outdoor activities nearby, including fishing and boating on the area's lakes, Interlachen offers a delightful escape from the hustle and bustle of city life.
  2. WaldoOpens in a new window: Waldo is a quaint little town with a reputation for its friendly people and inviting atmosphere. It's an excellent choice for those who appreciate small-town charm and want to experience a slower pace of life. While you're here, check out the local shops and markets that often feature handmade crafts and unique goods. The community spirit shines through, making Waldo a pleasant place to stay for those looking to connect with locals and enjoy a laid-back getaway.
  3. FlorahomeOpens in a new window: Florahome is a hidden gem that offers a unique blend of natural beauty and tranquility. It's perfect for travelers seeking a peaceful retreat surrounded by lush greenery and serene lakes. Enjoy outdoor activities like kayaking or hiking in the nearby nature preserves. The small-town atmosphere allows for a more personal experience, where you can easily engage with friendly locals and discover the area's hidden treasures. Florahome is ideal for those looking to escape the crowds and enjoy a relaxing stay in a picturesque setting.

Things to do in and around Melrose

Melrose is a hidden gem boasting stunning lakes, serene rivers, and lush parks, perfect for outdoor enthusiasts. Travelers can enjoy a variety of activities like hiking through scenic trails, golfing on verdant courses, or relaxing on sandy beaches. With recreational areas for family fun and opportunities for learning, it's an ideal spot for an unforgettable getaway.

  • Lake Como United Methodist ChurchOpens in a new window – Visit this charming church nestled in the heart of Melrose. It's a peaceful place to reflect and enjoy the serene surroundings, making it a perfect stop for those seeking a moment of tranquility.
  • Gold Head Branch State ParkOpens in a new window – Explore the natural beauty of this national state park, where you can hike along scenic trails, picnic by the lake, or simply soak in the stunning views of the lush landscape. Bring your camera to capture the wildlife and picturesque scenery!
  • Mike Roess Gold Head Branch State ParkOpens in a new window – This nearby gem offers additional opportunities for outdoor activities. Wander through its diverse ecosystems, take a leisurely stroll along the river, or enjoy a day of fishing in the tranquil waters.
  • Samuel P. Harn Museum of ArtOpens in a new window – Spend some time at this art museum, where you can admire a rich collection of artwork. From contemporary pieces to classic exhibits, there's something to inspire everyone. Check out any special events or exhibits that might be happening during your visit.
  • Ben Hill Griffin StadiumOpens in a new window – If you're a sports enthusiast, don’t miss the chance to visit this historic stadium. It's a hub of excitement on game days, so catch a game if you can, or simply take a tour to learn about its significance in the local sports scene.

5 tips for savvy savings when booking a hotel in Melrose

  1. Book for the cheapest times: The most budget-friendly time to visit Melrose is during January, July, and December, when hotel prices tend to be lower. For a great value experience, it’s recommended to stay for at least 2 to 3 days to fully explore the city’s rich history and culture. During your visit, you can enjoy various attractions including the historic tower, art gallery, heritage railway, and courthouse. Don’t miss the opportunity to visit the iconic modern civic government building and the local sports museum, which showcase the area's unique cultural heritage. With so much to see, this affordable getaway will provide an enriching experience for travelers on a budget.
  2. Instant discounts. Rewards for later: Save up to 20% instantly on hundreds of thousands of properties with Member Discounts. Then earn rewards on eligible stays to use on future trips. Book once, win twice, get instant discounts and rewards. Join for freeOpens in a new window.
  3. Score last-minute deals on Hotels.com: Last-minute travel doesn't mean last-minute stress. Hotels.com's Last-Minute DealsOpens in a new window offer discounted rates close to your travel date, so the later you leave it, the more you could save. Turn on push notifications and you'll be the first to know when dealsOpens in a new window drop for Melrose.
  4. Book with confidence, not guesswork: Prices in Melrose shift with the season, local events, and how far out you book — but you don't have to guess. Hotels.com shows you the full price upfront with no surprises at checkout, and our price tracker tells you whether your dates are above or below average. So if you're flexible, you can shift your trip by a day or two to avoid peak season prices, compare pricesOpens in a new window and know you're getting a good deal before you commit.
  5. Think beyond the city center: Central hotels may come with a central price tag. A well-connected neighborhood a little further out may cut your hotel bill and can often give you a more local experience. Use Hotels.com's map view to find the sweet spot between location and value, and filter by price to see what's available across Melrose.

Best time to go to Melrose

Melrose experiences its lowest average temperature in January, at 55.8°F (13.2°C), while July to August are the hottest months, with an average temperature of 81.5°F (27.5°C). August is typically the wettest month. If you’re looking to soak up the lively atmosphere in Melrose, April, July, and September are the peak months to visit, bustling with fellow travelers. During this peak period, the weather is mostly sunny, with light rainfall. However, if you prefer a more relaxed experience, October to December are perfect for a quieter getaway, marked by light rainfall and mostly sunny conditions.

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