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Hotels in Cape Girardeau

your current months are February, 2025 and March, 2025.
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March 2025
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Where to stay in Cape Girardeau?

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Cape Girardeau

Learn more about Cape Girardeau

Cape Girardeau is well known for its riverfront and university life, while attractions include Riverfront Park and Isle Casino Cape Girardeau. Visitors to this family-friendly city speak highly of the restaurants whereas sights include Riverfront Bridge Park and Show Me Center.

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Frequently asked questions

Can I book a refundable accommodation option in Cape Girardeau?
If you want the flexibility to change your plans to Cape Girardeau, most hotels offer refundable* rates that you can book. You can find these properties by searching our site and using the “fully refundable” filter to narrow down the results.
Where can I stay in Cape Girardeau if I want a holiday rental instead of a hotel?
If you want to find a good alternative to a hotel, review our selection of 22 holiday homes. In addition, you can choose from 12 apartments.
What will the weather in Cape Girardeau be like during my visit?
July and August are typically the warmest months in Cape Girardeau, when the average temperature is 25°C. January and February are the coldest months, when the average temperature is 5°C. April and March are the months with the most rain.
Why should I book my Cape Girardeau hotel with Hotels.com?
There are lots of reasons to book your Cape Girardeau trip with us: our free cancellations on selected hotels* gives you flexibility, our Price Guarantee ensures that you always get the lowest price, and you can earn rewards on every booking.