The Spa at Sanibel Harbour has 24 treatment rooms, including rooms for couples. Services include deep-tissue massages, hot stone massages, sports massages and Swedish massages. A variety of treatment therapies are provided, including aromatherapy, Ayurvedic and reflexology. The spa is equipped with a sauna and a steam room.
The spa is open daily. Guests under 16 years old are not allowed in the spa.