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Where to stay in Chaffee?
Properties are selected based on real traveller reviews and popularity among guests who’ve booked a night in Chaffee on Hotels.com. These Chaffee hotels consistently deliver on quality, location and traveller experience. Last updated on 15 November 2026.

1. Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (242 reviews)
The price is AU$143
includes taxes & fees
29 Nov - 30 Nov

2. Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (1,004 reviews)
The price is AU$150
includes taxes & fees
19 Nov - 20 Nov

3. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGCape Girardeau
9.4 out of 10, Exceptional, (1,000 reviews)
The price is AU$160
includes taxes & fees
13 Dec - 14 Dec

4. Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau WestCape Girardeau
9.2 out of 10, Wonderful, (1,005 reviews)
The price is AU$120
includes taxes & fees
22 Nov - 23 Nov

5. Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
9.6 out of 10, Exceptional, (1,006 reviews)
The price is AU$167
includes taxes & fees
19 Nov - 20 Nov

6. Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 EastCape Girardeau
9.6 out of 10, Exceptional, (861 reviews)
The price is AU$163
includes taxes & fees
22 Nov - 23 Nov

7. Candlewood Suites Cape Girardeau by IHG
Candlewood Suites Cape Girardeau by IHGCape Girardeau
8.0 out of 10, Very good, (1,003 reviews)
The price is AU$123
includes taxes & fees
25 Nov - 26 Nov

8. Tru By Hilton Cape Girardeau
Tru By Hilton Cape GirardeauCape Girardeau
9.6 out of 10, Exceptional, (201 reviews)
The price is AU$143
includes taxes & fees
22 Nov - 23 Nov

9. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape GirardeauJackson
8.8 out of 10, Excellent, (898 reviews)
The price is AU$128
includes taxes & fees
22 Nov - 23 Nov

10. Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau DowntownCape Girardeau
9.6 out of 10, Exceptional, (562 reviews)
The price is AU$194
includes taxes & fees
29 Nov - 30 Nov

11. The Riverview
The RiverviewCape Girardeau
9.4 out of 10, Exceptional, (705 reviews)
The price is AU$189
includes taxes & fees
16 Nov - 17 Nov

12. Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MOJackson
9.6 out of 10, Exceptional, (1,003 reviews)
The price is AU$125
includes taxes & fees
22 Nov - 23 Nov

13. Quality Inn Cape Girardeau North
Quality Inn Cape Girardeau NorthCape Girardeau
7.0 out of 10, Good, (824 reviews)
The price is AU$99
includes taxes & fees
22 Nov - 23 Nov

14. Comfort Suites Jackson-Cape Girardeau
Comfort Suites Jackson-Cape GirardeauJackson
8.0 out of 10, Very good, (786 reviews)
The price is AU$120
includes taxes & fees
13 Dec - 14 Dec

15. Best Western Plus Sikeston I-55
Best Western Plus Sikeston I-55Sikeston
8.4 out of 10, Very good, (1,002 reviews)
The price is AU$118
includes taxes & fees
14 Dec - 15 Dec

16. Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott SikestonSikeston
9.4 out of 10, Exceptional, (118 reviews)
The price is AU$185
includes taxes & fees
21 Nov - 22 Nov

17. Hampton Inn Sikeston
Hampton Inn SikestonSikeston
9.0 out of 10, Wonderful, (661 reviews)
The price is AU$168
includes taxes & fees
22 Nov - 23 Nov

18. Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHGSikeston
8.8 out of 10, Excellent, (528 reviews)
The price is AU$170
includes taxes & fees
29 Nov - 30 Nov

19. Town House Inn Cape Giradreau
Town House Inn Cape GiradreauCape Girardeau
6.2 out of 10, Good, (244 reviews)
The price is AU$121
includes taxes & fees
16 Nov - 17 Nov

20. TownePlace Suites by Marriott Sikeston
TownePlace Suites by Marriott SikestonSikeston
9.2 out of 10, Wonderful, (33 reviews)
The price is AU$183
includes taxes & fees
22 Nov - 23 Nov
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Go beyond your typical stay in Chaffee

Pet friendly

Pool
Learn more about Chaffee
The region around Chaffee is home to attractions such as Century Casino & Hotel Cape Girardeau and Cape Splash Family Aquatic Center.

Photo by Abbie Moon
Open Photo by Abbie Moon
































































