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Where to stay in Chaffee?
Properties are selected based on real traveller reviews and popularity among guests who’ve booked a night in Chaffee on Hotels.com. These Chaffee hotels consistently deliver on quality, location and traveller experience. Last updated on 12 November 2026.

1. Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (242 reviews)
The price is AU$165
includes taxes & fees
22 Nov - 23 Nov

2. Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (1,002 reviews)
The price is AU$147
includes taxes & fees
22 Nov - 23 Nov

3. Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
9.6 out of 10, Exceptional, (1,001 reviews)
The price is AU$163
includes taxes & fees
22 Nov - 23 Nov

4. Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau WestCape Girardeau
9.2 out of 10, Wonderful, (1,000 reviews)
The price is AU$117
includes taxes & fees
16 Nov - 17 Nov

5. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGCape Girardeau
9.4 out of 10, Exceptional, (1,000 reviews)
The price is AU$156
includes taxes & fees
11 Dec - 12 Dec

6. Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 EastCape Girardeau
9.6 out of 10, Exceptional, (860 reviews)
The price is AU$159
includes taxes & fees
22 Nov - 23 Nov

7. Candlewood Suites Cape Girardeau by IHG
Candlewood Suites Cape Girardeau by IHGCape Girardeau
8.0 out of 10, Very good, (1,002 reviews)
The price is AU$125
includes taxes & fees
22 Nov - 23 Nov

8. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape GirardeauJackson
8.8 out of 10, Excellent, (896 reviews)
The price is AU$125
includes taxes & fees
22 Nov - 23 Nov

9. Tru By Hilton Cape Girardeau
Tru By Hilton Cape GirardeauCape Girardeau
9.6 out of 10, Exceptional, (201 reviews)
The price is AU$140
includes taxes & fees
17 Nov - 18 Nov

10. The Riverview
The RiverviewCape Girardeau
9.4 out of 10, Exceptional, (703 reviews)
The price is AU$184
includes taxes & fees
23 Nov - 24 Nov

11. Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau DowntownCape Girardeau
9.6 out of 10, Exceptional, (559 reviews)
The price is AU$190
includes taxes & fees
22 Nov - 23 Nov

12. Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MOJackson
9.6 out of 10, Exceptional, (1,003 reviews)
The price is AU$122
includes taxes & fees
22 Nov - 23 Nov

13. Comfort Suites Jackson-Cape Girardeau
Comfort Suites Jackson-Cape GirardeauJackson
8.0 out of 10, Very good, (785 reviews)
The price is AU$119
includes taxes & fees
6 Dec - 7 Dec

14. Quality Inn Cape Girardeau North
Quality Inn Cape Girardeau NorthCape Girardeau
7.0 out of 10, Good, (821 reviews)
The price is AU$97
includes taxes & fees
22 Nov - 23 Nov

15. Best Western Plus Sikeston I-55
Best Western Plus Sikeston I-55Sikeston
8.4 out of 10, Very good, (1,009 reviews)
The price is AU$121
includes taxes & fees
7 Dec - 8 Dec

16. Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott SikestonSikeston
9.4 out of 10, Exceptional, (118 reviews)
The price is AU$182
includes taxes & fees
19 Nov - 20 Nov

17. Hampton Inn Sikeston
Hampton Inn SikestonSikeston
9.0 out of 10, Wonderful, (657 reviews)
The price is AU$167
includes taxes & fees
19 Nov - 20 Nov

18. Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHGSikeston
8.8 out of 10, Excellent, (525 reviews)
The price is AU$166
includes taxes & fees
23 Nov - 24 Nov

19. TownePlace Suites by Marriott Sikeston
TownePlace Suites by Marriott SikestonSikeston
9.2 out of 10, Wonderful, (32 reviews)
The price is AU$180
includes taxes & fees
19 Nov - 20 Nov

20. EC Reed's Mercantile and Hotel
EC Reed's Mercantile and HotelMarble Hill
9.4 out of 10, Exceptional, (118 reviews)
The price is AU$165
includes taxes & fees
22 Nov - 23 Nov
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Go beyond your typical stay in Chaffee

Pet friendly

Pool
Learn more about Chaffee
The region around Chaffee is home to attractions such as Century Casino & Hotel Cape Girardeau and Cape Splash Family Aquatic Center.

Photo by Abbie Moon
Open Photo by Abbie Moon
































































