Hotels in O Brien

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight
14 Nov - 15 Nov
Tomorrow
15 Nov - 16 Nov
Next weekend
20 Nov - 22 Nov
In two weeks
27 Nov - 29 Nov

Where to stay in O Brien?

Properties are selected based on real traveller reviews and popularity among guests who’ve booked a night in O Brien on Hotels.com. These O Brien hotels consistently deliver on quality, location and traveller experience. Last updated on 14 November 2026.
A multi-story hotel with a modern design, featuring a covered entrance and a parking lot.

1. Fairfield Inn & Suites Lake City

Fairfield Inn & Suites Lake City
3.0 star property
Lake City
9.0 out of 10, Wonderful, (300 reviews)
Wake up to complimentary breakfast at this Lake City hotel, where the indoor pool and spa pool create perfect relaxation spots. Just minutes from Regal UA Cinema 90 and local shopping, enjoy free WiFi and parking with business-friendly amenities.
The price is AU$155
includes taxes & fees
5 Dec - 6 Dec
Fairfield Inn & Suites Lake City
A hotel room with a gray sofa, a bed with white linens, a desk with a chair, and a window with blinds.

2. Comfort Suites Lake City

Comfort Suites Lake City
2.5 star property
Lake City
9.4 out of 10, Exceptional, (1,002 reviews)
Escape to this welcoming Lake City hotel where an outdoor pool provides refreshing relaxation. Located near Regal UA Cinema 90 and Lake City Mall, guests rave about the free breakfast and helpful staff.
The price is AU$155
includes taxes & fees
6 Dec - 7 Dec
Comfort Suites Lake City
A La Quinta hotel with a modern facade, multiple windows, and a well-lit entrance.

3. La Quinta Inn & Suite by Wyndham Lake City

La Quinta Inn & Suite by Wyndham Lake City
3.0 star property
Lake City
8.8 out of 10, Excellent, (1,210 reviews)
This business-friendly Lake City hotel offers 24-hour fitness options alongside free breakfast, WiFi, and parking. Near Regal UA Cinema 90 and Lake City Mall, the indoor pool invites year-round swimming after exploring local attractions.
The price is AU$155
includes taxes & fees
2 Dec - 3 Dec
La Quinta Inn & Suite by Wyndham Lake City
A spacious living area with a grey sofa, a coffee table, and a TV stand.

4. Best Western Plus Lake City

Best Western Plus Lake City
2.5 star property
Lake City
9.0 out of 10, Wonderful, (1,129 reviews)
Located minutes from Lake City Mall and Regal UA Cinema 90, this welcoming hotel offers an indoor pool and fitness centre. Enjoy free WiFi, parking, and breakfast before exploring the area. Business travellers appreciate the friendly staff.
The price is AU$132
includes taxes & fees
13 Dec - 14 Dec
Best Western Plus Lake City
A spacious indoor area with a pool view, multiple seating arrangements, and a central plant.

5. Hampton Inn & Suites Lake City

Hampton Inn & Suites Lake City
2.5 star property
Lake City
9.4 out of 10, Exceptional, (1,001 reviews)
Just off I-75, this welcoming hotel offers a refreshing outdoor pool and fitness centre near Regal UA Cinema 90 and Lake City Mall. Enjoy free breakfast, WiFi, and parking, while the helpful staff ensures a clean, comfortable business stay.
The price is AU$161
includes taxes & fees
13 Dec - 14 Dec
Hampton Inn & Suites Lake City
An outdoor patio with a stone fire feature, blue cushioned seating, and a grill.

6. Tru by Hilton Lake City

Tru by Hilton Lake City
2.5 star property
Lake City
9.2 out of 10, Wonderful, (1,001 reviews)
Dive into comfort at this Lake City hotel with an outdoor swimming pool. Work out in the fitness centre after enjoying a free breakfast. Near Regal UA Cinema 90 and Lake City Mall, with helpful staff and complimentary WiFi and parking.
The price is AU$154
includes taxes & fees
6 Dec - 7 Dec
Tru by Hilton Lake City
A hotel lobby with a reception desk, a clock, a plant, a water dispenser, and a coffee station.

7. Americas Best Value Inn Lake City

Americas Best Value Inn Lake City
2.0 star property
Lake City
8.6 out of 10, Excellent, (1,000 reviews)
Close to Regal UA Cinema 90 and Lake City Mall, this motel welcomes travellers with an outdoor pool and complimentary perks. Free WiFi, parking, and daily breakfast from 6:00 AM make for exceptional value.
The price is AU$118
includes taxes & fees
15 Nov - 16 Nov
Americas Best Value Inn Lake City
An outdoor patio with a stone fire pit, grey cushioned seating, and wicker ottomans.

8. Home2 Suites by Hilton Lake City

Home2 Suites by Hilton Lake City
3.0 star property
Lake City
9.4 out of 10, Exceptional, (834 reviews)
This quiet Lake City hotel offers convenient access to Regal UA Cinema 90 and Lake City Mall. Enjoy the outdoor pool, snack bar, and free breakfast. Rooms feature sofa beds and refrigerators, while a terrace and fitness centre enhance your peaceful stay.
The price is AU$196
includes taxes & fees
22 Nov - 23 Nov
Home2 Suites by Hilton Lake City
A compact kitchen with a blue refrigerator, a black coffee maker, a microwave, and a small black refrigerator.

9. Cindys Motel

Cindys Motel
2.5 star property
Mayo
8.8 out of 10, Excellent, (142 reviews)
Discover welcoming comfort at this cosy Mayo motel where attentive staff earn high praise from guests. Enjoy convenient free WiFi and parking, with daily housekeeping that ensures a refreshing stay near Veteran's Memorial Park.
The price is AU$139
includes taxes & fees
15 Dec - 16 Dec
Cindys Motel
A multi-story hotel with a modern design, featuring a prominent entrance and a parking area.

10. Courtyard By Marriott Lake City

Courtyard By Marriott Lake City
3.0 star property
Lake City
9.6 out of 10, Exceptional, (315 reviews)
Unwind at this Lake City gem with an outdoor pool and on-site café. Grab a drink at the bar after exploring Regal UA Cinema 90 and Lake City Mall. Business travellers will appreciate free WiFi and parking.
The price is AU$177
includes taxes & fees
22 Nov - 23 Nov
Courtyard By Marriott Lake City
An outdoor patio area with wicker chairs, a round table, and a fire pit.

11. TownePlace Suites by Marriott Lake City

TownePlace Suites by Marriott Lake City
3.0 star property
Lake City
9.6 out of 10, Exceptional, (152 reviews)
Unwind at this modern Lake City retreat offering both indoor and outdoor pools, free WiFi, and complimentary breakfast. Near local attractions like Regal UA Cinema 90 and Lake City Mall, this hotel includes convenient free parking for stress-free exploration.
The price is AU$213
includes taxes & fees
15 Nov - 16 Nov
TownePlace Suites by Marriott Lake City
A spacious lobby with a high ceiling, a large window, a dining area with green chairs, and a black door leading outside.

12. Quality Inn Lake City

Quality Inn Lake City
2.5 star property
Lake City
8.2 out of 10, Very good, (1,002 reviews)
Enjoy the outdoor pool and fitness centre at this welcoming Lake City lodging. Clean rooms provide restful stays near Regal UA Cinema 90 and Lake City Mall. The attentive staff, free breakfast, WiFi, and parking enhance your travel experience.
The price is AU$113
includes taxes & fees
13 Dec - 14 Dec
Quality Inn Lake City
Room

13. Super 8 by Wyndham Lake City

Super 8 by Wyndham Lake City
2.0 star property
Lake City
7.4 out of 10, Good, (769 reviews)
Dive into the refreshing outdoor pool at this Lake City motel. Enjoy free WiFi, complimentary parking, and cooked-to-order breakfast daily from 6-9 AM. Near North Florida Speedway and Southside Sports Complex, with staff that guests consistently praise for their helpfulness.
The price is AU$101
includes taxes & fees
1 Dec - 2 Dec
Super 8 by Wyndham Lake City
A multi-story hotel with a central entrance, palm trees, and a covered walkway.

14. Holiday Inn & Suites Lake City by IHG

Holiday Inn & Suites Lake City by IHG
3.0 star property
Lake City
8.6 out of 10, Excellent, (1,001 reviews)
At this Lake City hotel, unwind in the indoor pool after a workout in the 24-hour fitness centre. The Atrium restaurant serves American cuisine, while the bar offers evening relaxation. Located near Regal UA Cinema 90 and Lake City Mall with free WiFi and parking.
The price is AU$154
includes taxes & fees
13 Dec - 14 Dec
Holiday Inn & Suites Lake City by IHG
A buffet with various food items, including omelets and baked goods, served in metal containers.

15. Holiday Inn Express & Suites Live Oak by IHG

Holiday Inn Express & Suites Live Oak by IHG
2.5 star property
Live Oak
8.4 out of 10, Very good, (901 reviews)
This hotel offers a fitness centre and restaurant just minutes from Suwannee County Historical Museum. With free WiFi and parking, plus clean rooms praised by travellers, you'll find comfort near First Federal Sportsplex.
The price is AU$160
includes taxes & fees
13 Dec - 14 Dec
Holiday Inn Express & Suites Live Oak by IHG
A hotel room with two beds, a TV, a desk, and a painting of a sunset.

16. Days Inn by Wyndham Lake City I-75

Days Inn by Wyndham Lake City I-75
2.0 star property
Lake City
7.6 out of 10, Good, (1,000 reviews)
This Lake City hotel offers free continental breakfast, WiFi and parking, with nearby access to Regal UA Cinema 90 and Lake City Mall. Travellers praise the helpful staff and clean rooms during their comfortable, business-friendly stay.
The price is AU$111
includes taxes & fees
1 Dec - 2 Dec
Days Inn by Wyndham Lake City I-75
A modern kitchen with a large window, a flat-screen TV, and a coffee machine.

17. Quality Inn White Springs Suwanee

Quality Inn White Springs Suwanee
2.5 star property
White Springs
7.2 out of 10, Good, (710 reviews)
This relaxing Live Oak hotel offers easy access to Blue Sink Canoe Launch and nearby hiking trails. After outdoor adventures, unwind in the outdoor pool. Clean rooms, helpful staff, free breakfast, and complimentary parking enhance your stay.
The price is AU$98
includes taxes & fees
6 Dec - 7 Dec
Quality Inn White Springs Suwanee
A hotel room with two beds, a blue wall, and a window with curtains.

18. Gateway Inn

Gateway Inn
2.5 star property
Lake City
7.8 out of 10, Good, (213 reviews)
Unwind at this budget-friendly motel with daily housekeeping, close to Lake City Mall and area attractions. Free Wi-Fi keeps you connected while complimentary parking adds convenience for your North Florida adventure.
The price is AU$81
includes taxes & fees
15 Nov - 16 Nov
Gateway Inn
A kitchen counter with a coffee maker, a 'Welcome' sign, and a vase of flowers.

19. Driftwood Inn

Driftwood Inn
2.0 star property
Lake City
7.8 out of 10, Good, (810 reviews)
Inviting comfort awaits at this Lake City hotel near Regal UA Cinema 90 and Lake City Mall. Travellers praise the helpful staff and spotless rooms. Enjoy free parking and 24-hour front desk service during your stay.
The price is AU$95
includes taxes & fees
26 Nov - 27 Nov
Driftwood Inn
A reception area with a Baymont Inn & Suites sign, a reception desk, a glass-top table, and a door.

20. Baymont by Wyndham Lake City I-75

Baymont by Wyndham Lake City I-75
2.5 star property
Lake City
5.0 out of 10, (1,001 reviews)
Just off I-75, this welcoming hotel offers free breakfast, WiFi, and parking. Catch a film at nearby Regal UA Cinema 90 or shop at Lake City Mall. All rooms include refrigerators and microwaves for added convenience.
The price is AU$96
includes taxes & fees
15 Nov - 16 Nov
Baymont by Wyndham Lake City I-75
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Go beyond your typical stay in O Brien

pet-friendly image
Pet friendly
Pet friendly
Pool image
Pool
Pool

Learn more about O Brien

O Brien is well known for its attractions such as Suwannee River and Ichetucknee River.

See all hotels in O Brien
A calm river surrounded by trees reflecting in the water.

Check out reviews of O Brien hotels guests love

An outdoor patio with a stone fire feature, blue cushioned seating, and a grill.
Tru by Hilton Lake City

Tru by Hilton Lake City

Tru by Hilton Lake City
Lake City

10/10 Exceptional

Great location just off expressway. Friendly and helpful staff. Property in great condition and very clean. easy walk to food options. Loved the pool!
Australia
Rolando
Reviewed August 14, 2023
Tru by Hilton Lake City

Frequently Asked Questions

How much does a hotel room cost in O Brien?

You can choose a great hotel in O Brien from AU$81 with properties to suit all budgets and needs. To find an affordable hotel in O Brien that meets all of your requirements, just apply filters on Hotels.com and sort hotels by "Price: low to high".

How can I find deals and earn rewards at O Brien hotels?

Discover great deals on O Brien hotel stays with Hotels.com. Take a look at hotel prices mid-week or during the low season as to find those off-peak deals. If you're up for a spontaneous trip, don't forget to check out our last-minute deals on O Brien hotels.

Can I book O Brien hotels with free cancellation?

In order to book a refundable O Brien hotel, simply filter hotels by "Property cancellation options" and select "Fully refundable property". Most hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.

Keep exploring