Hotels in Eastern Panama

Free cancellation options if plans change
Earn rewards on every night you stay
Save more with Member Prices

Check prices for these dates

Tonight
20 Feb - 21 Feb
Tomorrow
21 Feb - 22 Feb
This weekend
21 Feb - 23 Feb
Next weekend
28 Feb - 2 Mar

Where to stay in Eastern Panama?

Cocoloco - Catamaran Lagoon 52F SAN BLAS
Exterior

Cocoloco - Catamaran Lagoon 52F SAN BLAS

3.0 star property
The price is AU$3,131
includes taxes & fees
9 Mar - 10 Mar
Cocoloco - Catamaran Lagoon 52F SAN BLAS
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Eastern Panama

Museum of the Kuna Nation

You can spend an afternoon browsing the exhibits at Museum of the Kuna Nation during your travels in Masargantupo. Stroll along the seaside or experience the area's festivals.

See properties in Museum of the Kuna Nation
Museum of the Kuna Nation

Learn more about Eastern Panama

Eastern Panama is well known for its attractions such as Cayos Holandeses and Chagres National Park. The city has something for everyone including sights like Darien National Park and Portobelo National Park within a tropical setting.

See all hotels in Eastern Panama

Frequently asked questions

Can I book a refundable accommodation option in Eastern Panama?
If you want the flexibility to change your plans to Eastern Panama, most hotels offer refundable* rates that you can book. You can find these properties by searching our site and using the “fully refundable” filter to narrow down the results.
Where can I stay in Eastern Panama if I want a holiday rental instead of a hotel?
If you want a good alternative to a hotel, review our selection of 14 holiday homes. You can also book one of the 16 cabins for your stay.
Why should I book my Eastern Panama hotel with Hotels.com?
There are plenty of reasons to book your Eastern Panama travel with us: our free cancellations on selected hotels* gives you the flexibility you’re looking for, our Price Guarantee ensures that you always get the lowest price, and you can earn rewards on every booking.