Photo by Martina

Hotels in Cayo Largo

your current months are January, 2025 and February, 2025.
January 2025
February 2025
Free cancellation options if plans change
Earn rewards on every night you stay
Save more with Member Prices

Where to stay in Cayo Largo?

Top landmarks in Cayo Largo

Cayo Largo del Sur

Cayo Largo del Sur

Cayo Largo del Sur is 2.4 mi (3.9 km) from central Cayo Largo, why not stop by during your stay?

See properties in Cayo Largo del Sur
Cayo Largo del Sur

Learn more about Cayo Largo

Cayo Largo is well known for its attractions such as Cayo Largo del Sur and Sirena Beach.

See all hotels in Cayo Largo
Photo by Martina
Open Photo by Martina

Frequently asked questions

Can I book a refundable accommodation option in Cayo Largo?
If you want the flexibility to change your plans to Cayo Largo, most hotels offer refundable* rates that you can book. You can find these properties by searching our site and using the “fully refundable” filter to narrow down the results.
What will the weather in Cayo Largo be like during my visit?
Cayo Largo is a great place to visit any time of year with an average temperature of 25°C during the coldest months.
Why should I book my Cayo Largo hotel with Hotels.com?
There are lots of reasons to book your Cayo Largo trip with us: our free cancellations on selected hotels* gives you flexibility, our Price Guarantee ensures that you always get the lowest price, and you can earn rewards on every booking.