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Hotels in Cayo Largo

Free cancellation options if plans change
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Check prices for these dates

Tonight
1 May - 2 May
Tomorrow
2 May - 3 May
This weekend
2 May - 4 May
Next weekend
9 May - 11 May

Where to stay in Cayo Largo?

Top landmarks in Cayo Largo

Cayo Largo del Sur

Cayo Largo del Sur

Cayo Largo del Sur is 2.4 mi (3.9 km) from central Cayo Largo, why not stop by during your stay?

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Cayo Largo del Sur

Learn more about Cayo Largo

Cayo Largo is well known for its attractions such as Cayo Largo del Sur and Sirena Beach.

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Frequently asked questions

Can I book a refundable accommodation option in Cayo Largo?
If you want the flexibility to change your plans to Cayo Largo, most hotels offer refundable* rates that you can book. You can find these properties by searching our site and using the “fully refundable” filter to narrow down the results.
What will the weather in Cayo Largo be like during my visit?
Cayo Largo is a great place to visit any time of year with an average temperature of 25°C during the coldest months.
Why should I book my Cayo Largo hotel with Hotels.com?
There are lots of reasons to book your Cayo Largo trip with us: our free cancellations on selected hotels* gives you flexibility, our Price Guarantee ensures that you always get the lowest price, and you can earn rewards on every booking.