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Hotels in Byron

October 2026
17
November 2026

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Next weekend
23 Oct - 25 Oct
In two weeks
30 Oct - 1 Nov

Where to stay in Byron?

Properties are selected based on real traveller reviews and popularity among guests who’ve booked a night in Byron on Hotels.com. These Byron hotels consistently deliver on quality, location and traveller experience. Last updated on 18 October 2026.
A spacious lobby with a reception desk, sofas, and a coffee table.
A Sleep Inn hotel with a covered entrance, stone pillars, and a clear blue sky.
A hotel room with a large bed, a sofa, a TV, and a desk.
A lobby with a brown sofa, yellow armchairs, a coffee table, and a clock on the wall.

1. Sleep Inn & Suites West-Near Medical Center

Sleep Inn & Suites West-Near Medical Center
Rochester
AU$127
includes taxes & fees
8 Nov - 9 Nov
Sleep Inn & Suites West-Near Medical Center
A Comfort Inn hotel with a stone facade, a covered entrance, and a parking area.
A hotel room with a blue sofa, a wooden coffee table, a bed with white linens, a TV, and a large mirror.
A spacious lobby with a central seating area, a reception desk, and a fireplace.
A spacious living room with a stone fireplace, blue sofas, and a flat-screen TV.

2. Comfort Inn & Suites West - Medical Center

Comfort Inn & Suites West - Medical Center
Rochester
AU$144
includes taxes & fees
8 Nov - 9 Nov
Comfort Inn & Suites West - Medical Center
A hotel reception desk with a wooden counter, a computer, and a vase with flowers.
A hotel room with a large bed, a view through a sliding glass door to an outdoor area, a nightstand with a lamp, and a wooden headboard.
A living room with stone walls, a fireplace, leather furniture, and a ceiling fan.
An indoor swimming pool with wooden beams and white chairs around it.

3. Baymont by Wyndham Kasson Rochester Area

Baymont by Wyndham Kasson Rochester Area
Kasson
AU$101
includes taxes & fees
25 Oct - 26 Oct
Baymont by Wyndham Kasson Rochester Area
A modern kitchen with dark wooden cabinets, a stainless steel refrigerator, a microwave, and a coffee maker. There is a dining area with two red chairs and a table.
An outdoor patio area with stone walls, outdoor seating, and landscaped gardens.
A compact hotel room with a kitchenette, a bed, a TV, and a seating area.
A compact hotel room with a kitchenette, a dining area, a seating area with a sofa and armchairs, and a large window with curtains.

4. Staybridge Suites Rochester - Commerce Dr NW by IHG

Staybridge Suites Rochester - Commerce Dr NW by IHG
Rochester
AU$217
includes taxes & fees
23 Oct - 24 Oct
Staybridge Suites Rochester - Commerce Dr NW by IHG
A modern dining area with high tables, chairs, and pendant lighting.
A reception desk with a large digital screen displaying a cityscape and the word "happy."
A hotel room with two beds, a desk with a computer, a chair, and a window with a view.
A swimming pool with a tiled deck, sun loungers, and a lifeguard chair.

5. Hampton Inn & Suites Rochester-North

Hampton Inn & Suites Rochester-North
Rochester
AU$170
includes taxes & fees
6 Nov - 7 Nov
Hampton Inn & Suites Rochester-North
An indoor swimming pool with a dolphin sculpture, wooden ceiling, and clear windows.
A hotel reception area with a coffee station, seating area, and a fireplace.
A hotel room with a large bed, two bedside tables with lamps, a telephone, and a window with sheer curtains.
A hotel room with a flat-screen TV, a sofa with a red pillow, a small table, and a lamp.

6. TownePlace Suites by Marriott Rochester

TownePlace Suites by Marriott Rochester
Rochester
AU$162
includes taxes & fees
24 Oct - 25 Oct
TownePlace Suites by Marriott Rochester
Room
A spacious living area with a wooden dining table, bar stools, and a patterned armchair. A staircase leads to an upper level with a balcony.
A spacious lobby with a high ceiling, a central seating area with patterned sofas and ottomans, a reception desk, and a staircase leading to an upper level.
A restaurant with a staircase, dining tables, chairs, a coffee machine, and a refrigerator.

7. Quality Inn near Medical Center

Quality Inn near Medical Center
Rochester
AU$104
includes taxes & fees
8 Nov - 9 Nov
Quality Inn near Medical Center
A hotel room with a large bed, a desk, a chair, a TV, and a window with curtains.
A reception area with a reception desk, two armchairs, a clock, and a framed artwork on the wall.
A Microtel Inn & Suites building with a signboard, a parking lot, and a clear sky.
A hotel room with a large window, a clock, a framed picture of pottery, a desk with a computer, and a seating area with patterned chairs.

8. Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic

Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
Rochester
AU$116
includes taxes & fees
1 Nov - 2 Nov
Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
A Holiday Inn Express building with a covered entrance, outdoor seating area, and a well-lit facade.
A reception desk with a wooden finish, a blue wall with the Holiday Inn Express logo, and a welcome sign for members.
A hotel dining area with multiple tables and chairs, a coffee station, and a seating area with sofas.
A coffee station with two espresso machines and a variety of coffee pods and cups.

9. Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG

Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
Kutzky Park
AU$158
includes taxes & fees
14 Nov - 15 Nov
Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
Room
A hotel reception area with a black reception desk, a 'WELCOME' sign, a bench, and two armchairs.
A compact kitchen with white cabinets, a microwave, a refrigerator, a sink, and a chair.
A multi-story hotel with a brick facade, a covered lobby entrance, and a parking lot with several cars.

10. Extended Stay America Suites Rochester North

Extended Stay America Suites Rochester North
Rochester
AU$100
includes taxes & fees
31 Oct - 1 Nov
Extended Stay America Suites Rochester North
An indoor swimming pool with slides, seating areas, and a covered section with umbrellas.
A modern kitchen with a microwave, sink, and granite countertop.
A modern kitchen with black cabinets, white countertops, and a tiled backsplash. There are pendant lights, a refrigerator, and a coffee machine.
A hotel room with two beds, a desk with a chair, a TV, and a window with curtains.

11. Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Rochester
AU$157
includes taxes & fees
26 Oct - 27 Oct
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
A modern indoor patio with a fire feature, seating, and large windows.
A modern hotel lobby with a large glass wall, a green wall mural, and a seating area with sofas and chairs.
A modern living room with a fireplace, large windows, and a flat-screen TV mounted on the wall.
A reception area with a curved reception desk, wooden shelving, and a green moss wall with the text "I ♥ EVEN".

12. EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG
Kutzky Park
AU$208
includes taxes & fees
24 Oct - 25 Oct
EVEN Hotel Rochester - Mayo Clinic Area by IHG
An outdoor patio area with a concrete floor, wooden fence, and string lights.
A breakfast bar with a wooden counter, a coffee machine, and a refrigerator.
Property amenity
A modern living room with a stone fireplace, a blue armchair, a round coffee table, and a large window offering a view of the outdoors.

13. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
Kutzky Park
AU$200
includes taxes & fees
6 Nov - 7 Nov
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
An outdoor patio area with yellow umbrellas, wicker furniture, and a sign for Centerstone Plaza Hotel.
A modern reception area with a wooden reception desk, glass pendant lights, and a long hallway with seating.
A garden with a water feature, rocks, and yellow umbrellas.
A modern living room with a dark wall, a decorative light fixture, and a patterned wall art piece.

14. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Historic Southwest
AU$189
includes taxes & fees
24 Oct - 25 Oct
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
A reception area with a wooden reception desk, a "Welcome to the Bread & Butter State" sign, and a "Please Center" sign.
A pool area with a table and chairs, a lifeguard chair, and a pool lift.
A modern lounge area with seating arrangements, a reception desk, and a patterned wall.
A hotel room with a bed, a desk, a chair, a TV, and a bathroom visible through an open door.

15. Hampton Inn Rochester-South

Hampton Inn Rochester-South
Rochester
AU$175
includes taxes & fees
24 Oct - 25 Oct
Hampton Inn Rochester-South
An outdoor seating area with a fire feature, blue cushioned chairs, and a modern building with large windows in the background.
A modern dining area with round tables and chairs, a large painting on the wall, and a flat-screen TV mounted above a geometric-patterned wall.
A modern bar area with seating and a counter.
A modern indoor pool area with lounge chairs and a pool.

16. Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area
Downtown Rochester
AU$196
includes taxes & fees
29 Oct - 30 Oct
Hyatt House Rochester/Mayo Clinic Area
A spacious outdoor dining area with modern furniture and large windows offering views of the city.
A modern interior with a wooden ceiling, a large black shelving unit, and a refrigerator stocked with beverages.
An outdoor dining area with wooden beams, tables, and chairs.
A modern hotel room with a large bed, a sofa, a small table, a desk, and a wardrobe.

17. Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG
Downtown Rochester
AU$177
includes taxes & fees
7 Nov - 8 Nov
Hotel Indigo Rochester – Mayo Clinic Area by IHG
An outdoor patio with a brick floor, stone fireplace, and wooden pergola.
An indoor swimming pool with clear pool rules posted on the wall, a lifeguard chair, and a pool lift sign.
A modern hotel lobby with a stone wall fireplace, comfortable seating, and a chandelier.
A conference room with multiple tables and chairs, ceiling fans, and artwork on the walls.

18. Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys
Kutzky Park
AU$196
includes taxes & fees
6 Nov - 7 Nov
Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys
A self-service breakfast station with a waffle maker, coffee machines, and a variety of condiments.
A hotel lobby with leather sofas, a stone fireplace, and a patterned carpet.
A compact laundry area with a washing machine, dryer, and a water fountain.
A hotel room with a large bed, a desk, a chair, a television, and a window with curtains.

19. Econo Lodge Mayo Clinic Area

Econo Lodge Mayo Clinic Area
Rochester
AU$110
includes taxes & fees
8 Nov - 9 Nov
Econo Lodge Mayo Clinic Area
A modern outdoor seating area with a built-in fireplace, two wooden chairs, a table, and a sofa.
A modern kitchen with a central island, bar stools, and pendant lighting. A living area with a sofa, ottoman, and a view of the outdoors is visible.
A hotel room with a kitchenette, a bed, a sofa, a small table, and a window with curtains.
A gym with various exercise equipment, including treadmills, stationary bikes, and weight machines.

20. Staybridge Suites Rochester - Mayo Clinic Area by IHG

Staybridge Suites Rochester - Mayo Clinic Area by IHG
Kutzky Park
AU$192
includes taxes & fees
1 Nov - 2 Nov
Staybridge Suites Rochester - Mayo Clinic Area by IHG
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Go beyond your typical stay in Byron

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Pet friendly
Pet friendly
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Pool
Pool
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Spa
Spa
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Spa pool
Spa pool
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Apart hotel
Apart hotel
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Apart­ment
Apart­ment
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Family friendly
Family friendly

Top landmarks in Byron

Oxbow Park

8.8/10 (5 reviews)
Oxbow Park is 3.4 mi (5.5 km) from central Byron, why not stop by during your stay? Our travellers also like this walkable area for its restaurants. If you like Oxbow Park, you'll love Douglas State Trail Head Rochester, just a short drive away.
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Community Center Park

Community Center Park is worth a visit when in central Byron.
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Tweite's Pumpkin Patch

Tweite's Pumpkin Patch is worth a visit, located 1.7 mi (2.7 km) from central Byron.
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Byron Town Square

If you like shopping, take time out to go to Byron Town Square when in Byron. Splash some more cash at High Point Shopping Center.
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High Point Shopping Center

If you like shopping, take time out to go to High Point Shopping Center when in Byron. Splash some more cash at Byron Town Square.
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Zollman Zoo

It's feeding time at the zoo! If you want to be reminded of some of the great animals our world is home to, you might want to pay a visit to Zollman Zoo, located 3.5 mi (5.7 km) from central Byron. If you'd also like to explore some of the parks in Byron, Oxbow Park is a short walk away.
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Somerby Golf Club

You might want to practise your swing at Somerby Golf Club, a golf course located 1.2 mi (1.9 km) from central Byron. If Somerby Golf Club doesn't quite scratch your golfing itch, Putting Green, and Links of Byron Mini Golf are also nearby.
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Putting Green

You might want to play some rounds at Putting Green, located 1.2 mi (1.9 km) from central Byron. If Putting Green doesn't quite scratch your golfing itch, Somerby Golf Club, and Links of Byron Mini Golf are also nearby.
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Frequently Asked Questions

How much does a hotel room cost in Byron?

You can find top hotels in Byron from AU$91 with options to suit your budget and needs. To find an affordable hotel in Byron that meets all of your requirements, just apply filters on Hotels.com and sort hotels by "Price: low to high".

How can I find deals and earn rewards at Byron hotels?

Discover great deals on Byron hotel stays with Hotels.com. Take a look at hotel prices mid-week or during the low season as to find those off-peak deals. And make sure to check out our last-minute deals on Byron hotels.

Can I book Byron hotels with free cancellation?

To book a refundable Byron hotel on Hotels.com, just filter hotels by "Property cancellation options" and select "Fully refundable property". The majority of hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.

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