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Hotels in Roxana

November 2026
December 2026

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This weekend
23 Oct - 25 Oct
Next weekend
30 Oct - 1 Nov

Where to stay in Roxana?

Properties are selected based on real traveller reviews and popularity among guests who’ve booked a night in Roxana on Hotels.com. These Roxana hotels consistently deliver on quality, location and traveller experience. Last updated on 20 October 2026.
A modern lobby with patterned armchairs, a fireplace, and a large TV on the wall.
A garden with a stone wall, a wooden pergola, and yellow daffodils.
A hotel dining area with tables and chairs, a kitchen in the background, and large windows with curtains.
A modern lobby with a blue patterned carpet, a white sofa, patterned armchairs, and a decorative mirror.

1. Holiday Inn Express & Suites Edwardsville by IHG

Holiday Inn Express & Suites Edwardsville by IHG
Edwardsville
AU$202
includes taxes & fees
19 Nov - 20 Nov
Holiday Inn Express & Suites Edwardsville by IHG
A hotel lobby with blue seating, a flat-screen TV, and a fireplace.
A reception area with two dark wooden reception desks, a stone-textured wall, and a sign reading "Comfort INN".
A spacious dining area with high tables and booths, large windows, and a view of greenery outside.
An indoor swimming pool with clear water, surrounded by lounge chairs and a tiled deck.

2. Comfort Inn Edwardsville - St. Louis

Comfort Inn Edwardsville - St. Louis
Edwardsville
AU$148
includes taxes & fees
26 Oct - 27 Oct
Comfort Inn Edwardsville - St. Louis
A brick building with a wooden gazebo in front.
A spacious dining area with multiple round tables and chairs, a fireplace, and large windows with curtains.
A statue of a Native American figure with a horse, a Route 66 sign, a map, and a clock on the wall.
A hotel room with two beds, a dresser, a television, and a bathroom visible through an open door.

3. Country Hearth Inn & Suites Edwardsville St. Louis

Country Hearth Inn & Suites Edwardsville St. Louis
Edwardsville
AU$214
includes taxes & fees
20 Oct - 21 Oct
Country Hearth Inn & Suites Edwardsville St. Louis
A hotel room with a bed, a desk with a TV, a chair, a sofa, and a window with curtains.
A conference room with a long table, six chairs, a flat-screen TV, and three framed artworks on the wall.
Breakfast area
Pool

4. Hampton Inn & Suites St. Louis/Alton

Hampton Inn & Suites St. Louis/Alton
Alton
AU$214
includes taxes & fees
26 Oct - 27 Oct
Hampton Inn & Suites St. Louis/Alton
A modern living room with a stone fireplace, a reception desk, and a large window.
A modern living room with a stone fireplace, green and beige sofas, a round coffee table, and large windows offering a view of trees.
A Fairfield by Marriott hotel with a modern design, featuring a covered entrance and multiple floors.
An indoor swimming pool with clear blue water, surrounded by lounge chairs and tables, large windows with a view of trees, and a tiled floor.

5. Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City

Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City
Granite City
AU$193
includes taxes & fees
26 Oct - 27 Oct
Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City
A modern bathroom with a red bathtub, a white sink, and a shower. There is a bed with a white mattress and a grey curtain in the adjacent room.
A modern kitchen with stainless steel appliances, a white countertop, and a framed picture on the wall.
A modern room with a stone wall, a flat-screen TV, two red chairs, a small table, and a view of the outside.
A modern kitchen area with a dining table and chairs, a refrigerator, a coffee machine, and a vending machine.

6. Red Lion Inn & Suites Pontoon Beach

Red Lion Inn & Suites Pontoon Beach
Granite City
AU$117
includes taxes & fees
20 Oct - 21 Oct
Red Lion Inn & Suites Pontoon Beach
A hotel entrance with a covered driveway and a parking area.
A hotel room with two desks, each with a computer, a lamp, and a chair.
A dining area with multiple tables and chairs, a kitchen in the background, and artwork on the walls.
A hotel lobby with striped armchairs, a round coffee table, a sofa, and a clock on the wall.

7. Best Western Plus Parkway Hotel

Best Western Plus Parkway Hotel
Alton
AU$151
includes taxes & fees
1 Nov - 2 Nov
Best Western Plus Parkway Hotel
A lobby with a blue sofa, patterned cushions, a reception desk, and a mural of a moon and arch.
A hotel with a central entrance, multiple floors, and a clear sky.
A hotel room with a bed, a sofa, a desk, and a television.
A breakfast bar with a microwave, coffee makers, and a fruit display.

8. La Quinta Inn & Suites by Wyndham Pontoon Beach

La Quinta Inn & Suites by Wyndham Pontoon Beach
Granite City
AU$197
includes taxes & fees
20 Oct - 21 Oct
La Quinta Inn & Suites by Wyndham Pontoon Beach
A multi-story hotel with balconies, a parking lot with marked spaces, and a clear sky.
A red door with a prohibition sign against tobacco, e-cigarettes, and cannabis.
A long, straight corridor with a series of doors on one side and a black railing on the other.
A hotel room with two beds, each with a wooden headboard, white bedding, and a patterned bedspread.

9. Bel Air Motel

Bel Air Motel
Wood River
AU$135
includes taxes & fees
20 Oct - 21 Oct
Bel Air Motel
An outdoor patio area with multiple tables and chairs, surrounded by neatly trimmed bushes and a gravel path.
A modern building with a blue and white color scheme, labeled "The Great Rivers." It features a parking lot with several cars and a gas station in the foreground.
A parking area with electric vehicle charging stations, marked parking spaces, and a chain-link fence.
A hotel lobby with a minibar, a refrigerator stocked with beverages, and a coffee station.

10. The Great Rivers, an Ascend Collection Hotel

The Great Rivers, an Ascend Collection Hotel
Alton
AU$148
includes taxes & fees
15 Nov - 16 Nov
The Great Rivers, an Ascend Collection Hotel
A Holiday Inn Express & Suites building with a modern design, featuring a covered entrance and a landscaped area with trees.
A modern hotel corridor with a wooden reception desk, a staircase, and a snack bar with various packaged foods.
Two reception desks with a modern design, a blue geometric wall in the background, and a sign indicating the hotel name.
A modern breakfast area with a counter displaying various food items and a sign reading "EXPRESS START BREAKFAST".

11. Holiday Inn Express and Suites Alton St Louis Area by IHG

Holiday Inn Express and Suites Alton St Louis Area by IHG
Alton
AU$200
includes taxes & fees
1 Nov - 2 Nov
Holiday Inn Express and Suites Alton St Louis Area by IHG
A spacious lobby with a high ceiling, large windows, and a variety of seating options including sofas and chairs.
A restaurant with a brick wall, large windows, and a seating area with tables and chairs.
A spacious indoor area with a large table and chairs, a sofa, and a staircase leading to an upper level.
An indoor swimming pool with clear glass walls, a tiled edge, and a ceiling with metal beams. There are lounge chairs and tables around the pool area.

12. Drury Inn & Suites St. Louis Collinsville

Drury Inn & Suites St. Louis Collinsville
Eastport
AU$162
includes taxes & fees
1 Nov - 2 Nov
Drury Inn & Suites St. Louis Collinsville
An indoor swimming pool with a lifeguard chair, a lifebuoy, and a mural of a beach scene.
A hotel room with two beds, a desk with a TV, a chair, and a window with a view of the outside.
A reception desk with a wooden counter, two HP laptops, a telephone, and a framed black and white photo on the wall.
A hotel room with a bed, a desk, a chair, a lamp, a mirror, and a television.

13. Super 8 by Wyndham Troy IL/St. Louis Area

Super 8 by Wyndham Troy IL/St. Louis Area
Troy
AU$102
includes taxes & fees
25 Oct - 26 Oct
Super 8 by Wyndham Troy IL/St. Louis Area
A hotel room with a bed, a desk with a television, a chair, a desk lamp, and a wall-mounted rack with keys.
Lobby
A hotel lobby with a reception desk, seating area, and a bakery display.
A modern office space with a desk, computer, and a large window.

14. Red Roof Inn St Louis - Troy, IL

Red Roof Inn St Louis - Troy, IL
Troy
AU$104
includes taxes & fees
25 Oct - 26 Oct
Red Roof Inn St Louis - Troy, IL
An outdoor patio area with wicker furniture, a stone fire pit, and potted plants.
A hotel reception area with a buffet counter, a fruit bowl, and a tiled floor.
A spacious lobby with a large sofa, armchairs, and a coffee table. There is a reception desk with a computer and a large decorative mirror.
A hotel room with two beds, a desk with a lamp, a television, and a coffee maker.

15. DoubleTree by Hilton Collinsville - St. Louis

DoubleTree by Hilton Collinsville - St. Louis
Eastport
AU$204
includes taxes & fees
26 Oct - 27 Oct
DoubleTree by Hilton Collinsville - St. Louis
A buffet area with a wooden counter, various food items, and a coffee station.
A reception area with a wooden reception desk, a stone wall with a clock, and framed pictures on the wall.
A Comfort Inn hotel with a simple facade, a parking lot, and a clear sky in the background.
A hotel room with two beds, a sofa, a desk, and a window with curtains.

16. Comfort Inn Collinsville near St. Louis

Comfort Inn Collinsville near St. Louis
Eastport
AU$176
includes taxes & fees
1 Nov - 2 Nov
Comfort Inn Collinsville near St. Louis
A modern hotel room with a large bed, a blue chair, and a wall-mounted TV.
A multi-story hotel with a covered entrance, a flagpole, and a parking lot.
A modern hotel lobby with a kitchen area, multiple seating arrangements, and framed artwork on the walls.
A reception desk with a Days Inn logo, a digital screen, and a telephone.

17. Days Inn by Wyndham Collinsville/St. Louis

Days Inn by Wyndham Collinsville/St. Louis
Eastport
AU$97
includes taxes & fees
12 Nov - 13 Nov
Days Inn by Wyndham Collinsville/St. Louis
A rooftop terrace with wicker furniture, offering a city view.
A spacious lobby with a blue sofa, a glass coffee table, and a chandelier.
A modern hotel lobby with a bar area, seating arrangements, and a large chandelier.
A lobby with seating areas, a chandelier, and a large pillar.

18. Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch
Downtown St. Louis
AU$227
includes taxes & fees
25 Oct - 26 Oct
Drury Plaza Hotel St. Louis at the Arch
A reception area with a counter, a digital screen, and a cityscape painting.
A reception area with a coffee station, seating, a TV, and a staircase.
A hotel room with two beds, a desk, and a window with curtains.
Vending machines with Coca-Cola branding and a sign advising not to fill ice chests.

19. Motel 6 Troy, IL

Motel 6 Troy, IL
Troy
AU$112
includes taxes & fees
2 Nov - 3 Nov
Motel 6 Troy, IL
A multi-story hotel with a covered entrance, stone pillars, and a parking lot.
A lobby with seating, a reception desk, and a snack area.
A hotel room with a bed, desk, chair, TV, and a minibar.
A counter with a coffee machine, condiment dispensers, and a display case with pastries.

20. La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

La Quinta Inn & Suites by Wyndham Collinsville - St. Louis
Eastport
AU$158
includes taxes & fees
1 Nov - 2 Nov
La Quinta Inn & Suites by Wyndham Collinsville - St. Louis
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Go beyond your typical stay in Roxana

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Pet friendly
Pet friendly
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Pool
Pool
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Spa
Spa
spa pool image
Spa pool
Spa pool
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Apart­ment
Apart­ment
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Family friendly
Family friendly
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Cottage
Cottage
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Villa
Villa

Top landmarks in Roxana

Wood River Refinery History Museum

Wood River Refinery History Museum is 0.8 mi (1.3 km) from central Roxana, why not stop by during your stay? If you want to experience more of the culture Roxana has to offer, head to Lewis and Clark Confluence Tower, Lewis and Clark Interpretive Center, and Jones-Confluence Point State Park.
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Charles Raich Field

You can catch an event at Charles Raich Field, located 0.7 mi (1.2 km) from central Roxana.
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Roxana Village Hall

Roxana Village Hall is worth a visit, located 1 mi (1.6 km) from central Roxana.
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Burbank Park

Burbank Park is worth a visit, located 1 mi (1.5 km) from central Roxana.
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Check out reviews of Roxana hotels guests love

A buffet area with a wooden counter, various food items, and a coffee station.
A reception area with a wooden reception desk, a stone wall with a clock, and framed pictures on the wall.
A Comfort Inn hotel with a simple facade, a parking lot, and a clear sky in the background.
A hotel room with two beds, a sofa, a desk, and a window with curtains.

Comfort Inn Collinsville near St. Louis

Comfort Inn Collinsville near St. Louis
Eastport

10/10 Exceptional

Australia
Marto
Comfort Inn Collinsville near St. Louis
A modern bathroom with a red bathtub, a white sink, and a shower. There is a bed with a white mattress and a grey curtain in the adjacent room.
A modern kitchen with stainless steel appliances, a white countertop, and a framed picture on the wall.
A modern room with a stone wall, a flat-screen TV, two red chairs, a small table, and a view of the outside.
A modern kitchen area with a dining table and chairs, a refrigerator, a coffee machine, and a vending machine.

Red Lion Inn & Suites Pontoon Beach

Red Lion Inn & Suites Pontoon Beach
Granite City

10/10 Exceptional

Australia
Hamilee
Red Lion Inn & Suites Pontoon Beach
A spacious lobby with modern seating, a reception desk, and large windows offering views of the parking area.
A seating area with three grey armchairs and a central glass-top table, a wooden floor, and a view of parked cars through large windows.
A spacious indoor area with a high ceiling and large windows, featuring multiple seating areas with sofas and chairs, and a visible outdoor view through the windows.
A spacious indoor area with multiple wooden tables and chairs, large windows, and a high ceiling with exposed beams.

Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport
St. Ann

10/10 Exceptional

Australia
Shayne
Pear Tree Inn St. Louis Airport
A rooftop terrace with wicker furniture, offering a city view.
A spacious lobby with a blue sofa, a glass coffee table, and a chandelier.
A modern hotel lobby with a bar area, seating arrangements, and a large chandelier.
A lobby with seating areas, a chandelier, and a large pillar.

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch
Downtown St. Louis

10/10 Exceptional

Australia
Wendy
Drury Plaza Hotel St. Louis at the Arch

Frequently Asked Questions

How much does a hotel room cost in Roxana?

You can find top hotels in Roxana from AU$94 with options to suit your budget and needs. If you're looking for an affordable hotel in Roxana that meets all of your requirements, just sort hotels by "Price: low to high" after applying your filters when searching on Hotels.com.

How can I find deals and earn rewards at Roxana hotels?

Discover great deals on Roxana hotel stays with Hotels.com. You can also look at hotel prices mid-week or during the low season to find off-peak deals. And make sure to check out our last-minute deals on Roxana hotels.

Can I book Roxana hotels with free cancellation?

To book a refundable Roxana hotel on Hotels.com, just filter hotels by "Property cancellation options" and select "Fully refundable property". Most hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.

What are some popular hotels in central Roxana?

If you're looking for hotels in central Roxana, check out TownePlace Suites by Marriott St. Louis Edwardsville, IL and Bel Air Motel. Travellers love TownePlace Suites by Marriott St. Louis Edwardsville, IL for its location, as well as the indoor pool, free buffet breakfast and 24-hour gym this hotel offers. Bel Air Motel is another popular central motel with free parking, plus free WiFi in the guestrooms.

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