Hotels in Roxana

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Where to stay in Roxana?

Properties are selected based on real traveller reviews and popularity among guests who’ve booked a night in Roxana on Hotels.com. These Roxana hotels consistently deliver on quality, location and traveller experience. Last updated on 7 September 2026.

1. The Great Rivers, an Ascend Collection Hotel

Alton

AU$138

includes taxes & fees

27 Sept - 28 Sept

2. Country Hearth Inn & Suites Edwardsville St. Louis

Edwardsville

AU$206

includes taxes & fees

8 Sept - 9 Sept

3. Holiday Inn Express & Suites Edwardsville by IHG

Edwardsville

AU$209

includes taxes & fees

20 Sept - 21 Sept

4. Comfort Inn Edwardsville - St. Louis

Edwardsville

AU$160

includes taxes & fees

27 Sept - 28 Sept

5. Best Western Plus Parkway Hotel

Alton

AU$127

includes taxes & fees

14 Sept - 15 Sept

6. TownePlace Suites by Marriott St. Louis Edwardsville, IL

Edwardsville

AU$257

includes taxes & fees

27 Sept - 28 Sept

7. Hampton Inn & Suites St. Louis/Alton

Alton

AU$206

includes taxes & fees

20 Sept - 21 Sept

8. Best Western Troy Hotel

Troy

AU$137

includes taxes & fees

14 Sept - 15 Sept

9. Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City

Granite City

AU$172

includes taxes & fees

20 Sept - 21 Sept

10. Red Lion Inn & Suites Pontoon Beach

Granite City

AU$113

includes taxes & fees

8 Sept - 9 Sept

11. Drury Inn & Suites St. Louis Collinsville

Eastport

AU$177

includes taxes & fees

14 Sept - 15 Sept

12. La Quinta Inn & Suites by Wyndham Pontoon Beach

Granite City

AU$190

includes taxes & fees

14 Sept - 15 Sept

13. Holiday Inn Express and Suites Alton St Louis Area by IHG

Alton

AU$193

includes taxes & fees

20 Sept - 21 Sept

14. Super 8 by Wyndham Troy IL/St. Louis Area

Troy

AU$105

includes taxes & fees

13 Sept - 14 Sept

15. Red Roof Inn St Louis - Troy, IL

Troy

AU$100

includes taxes & fees

14 Sept - 15 Sept

16. Comfort Inn Collinsville near St. Louis

Eastport

AU$168

includes taxes & fees

27 Sept - 28 Sept

17. Days Inn by Wyndham Collinsville/St. Louis

Eastport

AU$100

includes taxes & fees

13 Sept - 14 Sept

18. Pear Tree Inn St. Louis Airport

St. Ann

AU$147

includes taxes & fees

13 Sept - 14 Sept

19. Hyatt Select St. Louis Airport

Woodson Terrace

AU$188

includes taxes & fees

27 Sept - 28 Sept

20. Best Western St. Louis Airport North Hotel & Suites

Hazelwood

AU$137

includes taxes & fees

13 Sept - 14 Sept

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Go beyond your typical stay in Roxana

Pet friendly

Apartment

Pool

Spa pool

Cottage

Family friendly

Top landmarks in Roxana

Wood River Refinery History Museum

Wood River Refinery History Museum is 0.8 mi (1.3 km) from central Roxana, why not stop by during your stay? If you want to experience more of the culture Roxana has to offer, head to Lewis and Clark Interpretive Center, Dads Club Park, and Solid Impact Golf Center.

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Charles Raich Field

You can catch an event at Charles Raich Field, located 0.7 mi (1.2 km) from central Roxana.

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Roxana Village Hall

Roxana Village Hall is worth a visit, located 1 mi (1.6 km) from central Roxana.

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Burbank Park

Burbank Park is worth a visit, located 1 mi (1.5 km) from central Roxana.

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Check out reviews of Roxana hotels guests love

Hyatt Regency St. Louis at The Arch

10/10 Excellent

"Great staff, clean rooms. Didn't like the hotel parking, very crowded."

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

10/10 Excellent

"The guest before me got a tobacco smell in the carpet. The hotel cleaned it but couldn't get the smell out. They sprayed febreeze in the carpet and refunded me the full amount of the room. They even gave us some snacks and drinks for free."

Hilton St. Louis at the Ballpark

10/10 Excellent

"Did not know about the 360 until later on, I will definitely set up another stay. Hope to get a better view!"

Drury Inn & Suites St. Louis Airport

10/10 Excellent

"I loved my stay at the Drury! Check in was easy and the staff was friendly. Room was nice and clean. The shuttle from Lambert Airport to the hotel made it super convenient to get to since we didn't rent a car. Breakfast was good with lots of variety to choose from. Would stay again."

Drury Plaza Hotel St. Louis at the Arch

8/10 Good

"I enjoyed almost everything about my one-night stay at the Drury. My room and bed were comfortable with working air-conditioning. Staff was super friendly. The 5:30 kick back basically served an entire meal with 3 alcoholic beverages included. Because I had dinner reservations later, I only grabbed a hot dog and some coleslaw, but the drinks were very good and the food looked wonderful. The only reason I didn't give the hotel 5 stars was the check-in. If you are coming by car, there are two lanes in front of the hotel where you have to pull up on a very busy street (4th Street). I arrived 30 minutes before official check in time and the lanes were already full, so I had to circle the block a couple times. When I finally did get a spot and got checked in, I was trapped in the inner lane and had to wait for others to finish checking in before I could even proceed to the parking garage. Parking costs $32 and is in a poorly-designed garage with small spaces, many of which are partially taken up by support poles."

Clayton Plaza Hotel & Extended Stay

10/10 Excellent

"The only issue was the parking garage. One entrance was closed and you had to go around the block to park. I got a little confusing."

Forest Park Hotel by MDR

8/10 Good

"Parking was an issue"

Courtyard by Marriott St. Louis Downtown/Convention Center

10/10 Excellent

"Everything was super excellent"

Frequently asked questions

How much does a hotel room cost in Roxana?

You can find top hotels in Roxana with options to suit your budget and needs. If you're looking for an affordable hotel in Roxana that meets all of your requirements, just sort hotels by "Price: low to high" after applying your filters when searching on Hotels.com.

How can I find deals and earn rewards at Roxana hotels?

Discover great deals on Roxana hotel stays with Hotels.com. You can also look at hotel prices mid-week or during the low season to find off-peak deals. And make sure to check out our last-minute deals on Roxana hotels.

Can I book Roxana hotels with free cancellation?

To book a refundable Roxana hotel on Hotels.com, just filter hotels by "Property cancellation options" and select "Fully refundable property". Most hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.

What are some popular hotels in central Roxana?

If you're looking for hotels in central Roxana, check out TownePlace Suites by Marriott St. Louis Edwardsville, IL and Bel Air Motel. Travellers love TownePlace Suites by Marriott St. Louis Edwardsville, IL for its location, as well as the indoor pool, free buffet breakfast and 24-hour gym this hotel offers. Bel Air Motel is another popular central motel with free parking, plus free WiFi in the guestrooms.

Can I book a refundable accommodation option in Roxana?

If you want the flexibility to change your plans to Roxana, most hotels offer refundable* rates that you can book. You can see these properties by searching our site and using the "fully refundable" filter to narrow down the results.

What will the weather in Roxana be like during my visit?

July and August are typically the warmest months in Roxana, when the average temperature is 24°C. January and February are the coldest months, when the average temperature is 2°C. May and April are the months with the most rain.

Why should I book my Roxana hotel with Hotels.com?

There are lots of reasons to book your Roxana trip with us: our free cancellations on selected hotels* gives you flexibility, our Price Guarantee ensures that you always get the lowest price, and you can earn rewards on every booking.

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