4 Star Hotels in West Main Historic District

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Tonight
15 Oct - 16 Oct
Tomorrow
16 Oct - 17 Oct
This weekend
16 Oct - 18 Oct
Next weekend
23 Oct - 25 Oct

4 Star Hotels in West Main Historic District

Properties are selected based on real traveller reviews and popularity among guests who’ve booked a night in West Main Historic District on Hotels.com. These West Main Historic District 4 Star Hotels consistently deliver on quality, location and traveller experience. Last updated on 16 October 2026.
A classical gold statue in front of a multi-story building with large windows and a brick facade.

1. 21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
West Main Historic District
9.4 out of 10, Exceptional, (1,000 reviews)
The price is AU$264
includes taxes & fees
8 Nov - 9 Nov
21c Museum Hotel Louisville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Compare popular hotels in West Main Historic District

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
An indoor dining area with tables set for guests, surrounded by potted plants and hanging lights.
Hotel Distil, Autograph Collection
4.0 star property
9.6
Exceptional
510 reviews
View
A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.
Omni Louisville Hotel
4.0 star property
9.4
Exceptional
2,188 reviews
View
An outdoor seating area with sofas and tables, a fire feature, and a clock tower in the background.
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
4.0 star property
9.4
Exceptional
163 reviews
View
A classical gold statue in front of a multi-story building with large windows and a brick facade.
21c Museum Hotel Louisville
4.5 star property
9.4
Exceptional
1,000 reviews
View
A modern interior with a fireplace, bookshelves, a green sofa, and leather chairs.
The Grady
4.0 star property
9.4
Exceptional
1,014 reviews
View

Top landmarks in West Main Historic District

A river with a bridge, a stadium, and modern buildings.

KFC Yum Center

8.8/10 (1,621 reviews)
Imagine soaking up the atmosphere at KFC Yum Center, a stadium in Downtown Louisville. Why not take a stroll along the riverfront and watch the sunset while you're here? If you think KFC Yum Center is cool, you might also like Louisville Slugger Field and Lynn Family Stadium, both located nearby.
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Check out reviews of West Main Historic District hotels guests love

A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.
Omni Louisville Hotel

Omni Louisville Hotel

Omni Louisville Hotel
Downtown Louisville

10/10 Exceptional

The Omni was absolutely incredible - super luxurious feel to everything and the library and speakeasy bars were amazing. The staff were really helpful and friendly. The fall city market has everything you could need. The only downside is that we had planned to spend the afternoon at the pool bar, however it was closed all afternoon and evening for a private event - it would have been nice to know when making our booking to avoid the disappointment when we got there. Otherwise, can’t really...
Australia
Lauren
Reviewed October 12, 2024
Omni Louisville Hotel