Hotels in South Carolina Midlands
Free cancellation options if plans change
Earn rewards on every night you stay
Save more with Member Prices
Check prices for these dates
Where to stay in South Carolina Midlands?
Holiday Inn Express & Suites Latta by IHG
Holiday Inn Express & Suites Latta by IHGLatta
9.4 out of 10, Exceptional, (551 reviews)
- Seasonal pool and free breakfast add value to your Florence-adjacent stay.
The price is AU$182
includes taxes & fees
2 Mar - 3 Mar
Tru By Hilton Santee
Tru By Hilton SanteeSantee
9.2 out of 10, Wonderful, (720 reviews)
- Experience a comfortable stay near Santee Cooper Country Club with top-rated service.
The price is AU$171
includes taxes & fees
23 Feb - 24 Feb
Howard Johnson by Wyndham Florence
Howard Johnson by Wyndham FlorenceFlorence
8.6 out of 10, Excellent, (2,568 reviews)
- Convenient Florence stay with free parking near Darlington Raceway.
The price is AU$105
includes taxes & fees
18 Feb - 19 Feb
Baymont by Wyndham Santee
Baymont by Wyndham SanteeSantee
8.0 out of 10, Very good, (1,426 reviews)
- Relax in peaceful Santee with continental breakfast and helpful staff nearby.
The price is AU$117
includes taxes & fees
18 Feb - 19 Feb
Rodeway Inn Florence Downtown
Rodeway Inn Florence DowntownFlorence
6.0 out of 10, (2 reviews)
- Experience Florence's city centre convenience in a hotel near local attractions.
The price is AU$79
includes taxes & fees
16 Mar - 17 Mar
La Quinta Inn by Wyndham Columbia SE / Fort Jackson
La Quinta Inn by Wyndham Columbia SE / Fort JacksonColumbia
7.8 out of 10, Good, (1,002 reviews)
- Serene retreat near Fort Jackson with a seasonal pool for military families.
The price is AU$129
includes taxes & fees
15 Mar - 16 Mar
Springhill Suites by Marriott Columbia near Fort Jackson
Springhill Suites by Marriott Columbia near Fort JacksonColumbia
9.4 out of 10, Exceptional, (614 reviews)
- Stay at a modern Art Deco hotel near Fort Jackson with free breakfast daily.
The price is AU$155
includes taxes & fees
22 Feb - 23 Feb
Comfort Inn & Suites Florence Center Area
Comfort Inn & Suites Florence Center AreaFlorence
9.2 out of 10, Wonderful, (1,225 reviews)
- Sink into comfortable beds near Florence Veterans Park with a seasonal pool.
The price is AU$152
includes taxes & fees
15 Feb - 16 Feb
Southern Lodge 601
Southern Lodge 601Orangeburg
The price is AU$104
includes taxes & fees
15 Feb - 16 Feb
Best Western Plus Santee Inn
Best Western Plus Santee InnSantee
8.8 out of 10, Excellent, (1,002 reviews)
The price is AU$176
includes taxes & fees
15 Feb - 16 Feb
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHGFlorence
8.6 out of 10, Excellent, (1,007 reviews)
- Set among lush landscapes, this Florence hotel offers easy interstate access and relaxing poolside comfort.
The price is AU$187
includes taxes & fees
17 Feb - 18 Feb
SureStay Hotel by Best Western Manning
SureStay Hotel by Best Western ManningManning
8.6 out of 10, Excellent, (1,001 reviews)
- Just minutes from I-95, this hotel offers clean, comfortable accommodation.
The price is AU$140
includes taxes & fees
15 Feb - 16 Feb
Inn on the Square, an Ascend Collection Hotel
Inn on the Square, an Ascend Collection HotelUptown Greenwood
9.2 out of 10, Wonderful, (716 reviews)
- Boutique charm with southern hospitality in city centre Greenwood.
The price is AU$166
includes taxes & fees
15 Mar - 16 Mar
Hampton Inn Rock Hill
Hampton Inn Rock HillRock Hill
9.2 out of 10, Wonderful, (1,001 reviews)
The price is AU$140
includes taxes & fees
1 Mar - 2 Mar
Fairfield Inn & Suites by Marriott Santee
Fairfield Inn & Suites by Marriott SanteeSantee
9.8 out of 10, Exceptional, (1,003 reviews)
- Comfortable hotel in a tranquil setting, perfect for morning swims and golf outings.
The price is AU$190
includes taxes & fees
23 Feb - 24 Feb
Spark by Hilton Florence North I-95, SC
Spark by Hilton Florence North I-95, SCFlorence
8.0 out of 10, Very good, (47 reviews)
The price is AU$124
includes taxes & fees
24 Feb - 25 Feb
Upscale King 3BR Townhouse in Pineville
Upscale King 3BR Townhouse in PinevillePineville
The price is AU$299
includes taxes & fees
16 Feb - 17 Feb
Hyatt Place Florence Downtown
Hyatt Place Florence DowntownFlorence
9.0 out of 10, Wonderful, (1,001 reviews)
- Stay comfortably near Florence attractions with an outdoor pool and 24-hour fitness centre.
The price is AU$158
includes taxes & fees
2 Mar - 3 Mar
Best Inn of Manning
Best Inn of ManningManning
7.6 out of 10, Good, (15 reviews)
The price is AU$109
includes taxes & fees
19 Feb - 20 Feb
Best Western Plus Lexington Inn
Best Western Plus Lexington InnDowntown Lexington
9.2 out of 10, Wonderful, (1,000 reviews)
The price is AU$144
includes taxes & fees
15 Feb - 16 Feb
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Get last-minute hotel deals in South Carolina Midlands and save more
Sign in to unlock great savings.
Showing deals for:14 Feb - 15 Feb
9.4 out of 10, Exceptional, (299 reviews)
The price is AU$212
for 1 room
includes taxes & fees
Showing deals for:15 Feb - 16 Feb
9.0 out of 10, Wonderful, (1,098 reviews)
AU$16 off
The price is AU$143
for 1 room
includes taxes & fees
Showing deals for:20 Feb - 22 Feb
9.4 out of 10, Exceptional, (299 reviews)
AU$80 off
The price is AU$455
for 2 nights, 1 room
AU$227 per night
includes taxes & fees
You may also like pet-friendly hotels in South Carolina Midlands
The price is AU$171
includes taxes & fees
23 Feb - 24 Feb
You can also stay at hotels with a pool in South Carolina Midlands
9.0 out of 10, Wonderful, (672)
The price is AU$165
includes taxes & fees
22 Feb - 23 Feb
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Go beyond your typical stay in South Carolina Midlands
Top landmarks in Southeastern United States
Learn more about South Carolina Midlands
South Carolina Midlands is admired for its sports and university life, while top attractions include Fort Jackson and Carowinds Theme Park. The city has something for everyone including its live music, restaurants, and sights like Sesquicentennial State Park and Coopers Lake.
Check out reviews of South Carolina Midlands hotels guests love
La Quinta Inn by Wyndham Columbia NE/Fort Jackson
10/10 Excellent
Frequently asked questions
Keep exploring
- Royal Pines Estates Hotels
- Hotels near Trustus Theatre
- Hotels near Holy Trinity Greek Orthodox Church
- Hotels near Koger Center for the Arts
- Hotels near First Baptist Church
- Hotels near Palmetto Falls Water Park
- Hotels near Oak Hills Golf Club
- Hotels near Columbia Fire Museum
- Hotels near Columbia Regional Visitors Center
- Hotels near Saint Peter's Catholic Church
- Hotels near William Jennings Bryan Dorn Veterans Affairs Medical Center
- Hotels with Parking in St. Andrews
- Family Hotels in St. Andrews
- Hotels with Parking in Seven Oaks
- Hotels with Free Breakfast in Seven Oaks
- Cheap Hotels in Seven Oaks
- Cedar Creek Hotels
- Hotels with Parking in Leesville
- Hotels with Kitchens in Leesville
- Hotels with a Gym in Santee
- Pet Friendly Hotels in Santee
- Hotels with Parking in Blythewood
- Blythewood Hotels
- Hotels with Parking in Hartsville
- Hotels with Free Breakfast in Hartsville
- Hotels with a Gym in Irmo
- Hotels with a Pool in Camden
- Hotels with Parking in Camden
- Hotels with Kitchens in Camden
- Pet Friendly Hotels in Camden
- Cottages in Camden
- Hotels with Parking in Newberry
- Business Hotels in Newberry
- Hotels with Free Breakfast in Manning
- Pet Friendly Hotels in Manning
- Cheap Hotels in Manning
- Cottages in Chapin
- Hotels with Parking in Richburg
- Hotels with a Pool in West Columbia
- Hotels with Free Breakfast in West Columbia
- Cheap Hotels in West Columbia
- Hotels with a Pool in Columbia
- Hotels with a Gym in Columbia
- Hotels with Kitchens in Columbia
- Pet Friendly Hotels in Columbia
- Cottages in Columbia
- Motels in Columbia
- Cheap Hotels in Columbia
- Business Hotels in Columbia
- Family Hotels in Columbia
- Columbia Hotels
- Hotels with Free Breakfast in Orangeburg
- Pet Friendly Hotels in Orangeburg
- Cheap Hotels in Orangeburg
- Hotels with a Pool in Rock Hill
- Hotels with Parking in Rock Hill
- Hotels with a Gym in Rock Hill
- Pet Friendly Hotels in Rock Hill
- Motels in Rock Hill
- Cheap Hotels in Rock Hill
- Family Hotels in Rock Hill
- Hotels with a Pool in Sumter
- Hotels with Free Breakfast in Sumter
- Pet Friendly Hotels in Sumter
- Cheap Hotels in Sumter
- Hotels near Robert Mills Historic House and Park
- Hotels near University of South Carolina
- Hotels near Hampton-Preston Mansion and Gardens
- Hotels near Columbia Metropolitan Convention Center
- Hotels near Fort Jackson
- Hotels near Columbia Place Mall
- Hotels near Palmetto Health Richland Hospital
- Hotels with Parking in Dentsville
- Hotels with a Pool in Harbison
- Hotels with a Gym in Harbison
- Lgbtqia-Welcoming Hotels in Harbison
- Hotels with Parking in The Vista
- Business Hotels in The Vista
- The Vista Hotels
- Hotels near North Carolina Mutual Building
- Hotels near Booker T. Washington High School
- Hotels near Modjeska Monteith Simpkins House
- Hotels near Lutheran Theological Southern Seminary
- Hotels near Millwood Plantation Ruins
- Hotels near Soda City Market
- Shandon Hotels
- Cottages in South Carolina
- Apartments in South Carolina
- Cheap Hotels in South Carolina
- Luxury Hotels in South Carolina
- Business Hotels in South Carolina
- Beach Hotels in South Carolina
- Golf Hotels in South Carolina
- South Carolina Hotels