Properties are selected based on real traveller reviews and popularity among guests who’ve booked a night in Mytilene on Hotels.com. These Mytilene hotels consistently deliver on quality, location and traveller experience. Last updated on .
Hotels in Mytilene
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Where to stay in Mytilene?




Theofilos Paradise Boutique Hotel
Theofilos Paradise Boutique Hotel



Mythical Coast Wellness Retreat
Mythical Coast Wellness Retreat



Akti Vigla Premium
Akti Vigla Premium



Sunrise Resort Hotel
Sunrise Resort HotelCheck out pet-friendly hotels in Mytilene
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Go beyond your typical stay in Mytilene
Top landmarks in Mytilene
Mytilini Castle
Thermi Beach
St Hermogenes Charamida Lesvos
Thermes Gera Hot Springs
Roman Aqueduct at Moria
Archaeological Site of Thermi
Charamida Beach
Church of Taxiarches
Learn more about Mytilene
Notable for its seaside, Mytilene features attractions such as Port of Mytilene and Mytilini Castle.
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Check out reviews of Mytilene hotels guests love
Ampoulos Rooms & Apartments
"Very friendly family hotel"
Hotel Lesvion
"Amazing stay! From the location and view, the amenities, the delicious and extensive breakfast choices and to the incredible staff who helped me so kindly scanning documents and book a courier service for me. Beyond grateful for their help! I 100% recommend this hotel and will stay again in the future."
Lasia Hotel
"Lovely people, my only complaint is that the room was a bit outdated and the breakfast had few selections though the food quality was good. The staff could not have been more friendly or helpful and it is an excellent choice for location."
Blue Sea
"Long delay to check in however the hotel delivers a very clean environment, comfortable rooms and views and located in ideal location."
Theofilos Paradise Boutique Hotel
"Staff was nice. Large breakfast spread. Location is great."
Loriet Hotel
"Our vacation at the Loriet Hotel in Mithilini was amazing. Everything was perfect. We really had very good time in there. Thanks for the hospitality and the hygiene conditions. Having new plans for coming back again."
Agora Apartments
"Great facility, but do not use your car to reach the property. No close by parking, narrow streets. Great communication friendly staff. "
Paradisos studios
"This hotel is owner operated. Owner directly helped me to check in. Room was clean and spacious. Phenomenal value for the money. It is the 3rd time we have stayed at Paradisos. "
Frequently asked questions
Find out more about Mytilene
Whispers of History: Explore the Enchantment of Mytilene's Timeless Shores
Discover Mytilene, the vibrant capital of Lesvos, where rich history meets stunning landscapes. Wander through the charming streets of Mytilene Town, adorned with neoclassical architecture, and explore the imposing Mytilene Castle, which offers panoramic views of the Aegean Sea. Delve into the past at the Archaeological Museum of Mytilene, showcasing ancient artefacts and local treasures. Enjoy the serene beaches, lush olive groves, and delightful local cuisine, making it an ideal destination for culture enthusiasts and romantic getaways alike. Mytilene promises an unforgettable experience, blending history, nature, and captivating beauty in one enchanting locale.
Discover great hotels in Mytilene
Mytilene offers a variety of accommodations to suit all preferences, from budget-friendly hotels to more luxurious options. You'll find comfortable rooms, friendly service, and convenient locations, making it an ideal base for exploring the rich history and beautiful landscapes of Lesvos. Here are some of the most popular hotels with our travellers in Mytilene:
- Ariadnes Holiday AccommodationOpens in a new window: This charming guesthouse is an ideal choice for leisure travellers seeking a rejuvenating beach holiday. With direct access to the pristine shoreline, guests can immerse themselves in the sun and surf. The inviting atmosphere and well-appointed rooms ensure a comfortable stay, while the stunning coastal views enhance the overall experience. Travellers appreciate the serene environment, perfect for unwinding and enjoying the natural beauty of Mytilene.
- Ariadnes Holiday Accommodation IIOpens in a new window: Another excellent guesthouse option for those desiring a beach vacation, Ariadnes Holiday Accommodation II provides a seamless blend of relaxation and fun. Featuring direct access to the beach, it offers a perfect setting for sunbathing and water activities. The property’s inviting ambiance makes it a favourite among those looking to escape the hustle and bustle. Guests often highlight the tranquil surroundings and effortless access to the beach, creating a delightful retreat.
- Aeolis Apartments & StudiosOpens in a new window: This luxurious guesthouse caters to travellers looking for a distinctive spa and wellness experience, complete with pet-friendly options. The property boasts a natural hot spring nearby, allowing guests to indulge in relaxing hot spring amenities. With a full-service spa offering a variety of treatments and an outdoor pool, it is a haven for those seeking rejuvenation. Visitors frequently commend the exceptional spa services and the tranquil environment, making it an ideal sanctuary for relaxation and pampering.
Top locations to stay in Mytilene
When visiting Mytilene, Lesvos, North Aegean Islands, Greece, consider staying in Ano Chalikas, Lesvos, and Apidias Lakkos. Ano Chalikas offers a serene island atmosphere, while Lesvos is rich in museums and ancient ruins. Apidias Lakkos boasts beautiful island views. For first-time visitors, Lesvos is the best choice due to its cultural and historical significance.
- LesvosOpens in a new window: Lesvos is a captivating island renowned for its rich history and cultural heritage. This is a perfect base for exploring fascinating museums that showcase the island’s diverse history, from ancient ruins to Byzantine churches. Don't miss the chance to visit the picturesque villages, where you can enjoy local cuisine and vibrant markets. Lesvos also boasts stunning landscapes, making it ideal for leisurely hikes along the coast or through the lush countryside. The warmth of the locals and the island's unique charm create an inviting atmosphere for visitors seeking both relaxation and exploration.
- Ano ChalikasOpens in a new window: Ano Chalikas offers a tranquil retreat on the island of Lesvos, perfect for those looking to escape the hustle and bustle. With its beautiful island views and serene surroundings, this location is ideal for relaxation and unwinding. Visitors can enjoy leisurely strolls through the charming streets or take in the breathtaking sunsets over the Aegean Sea. It’s a great spot to immerse yourself in local culture and experience the authentic side of island life, away from the more touristy areas.
- Apidias LakkosOpens in a new window: Apidias Lakkos is a lesser-known gem on Lesvos that offers a peaceful atmosphere amidst stunning natural scenery. This area is perfect for those seeking a more laid-back experience, with opportunities for scenic walks and enjoying the beautiful coastal views. While smaller and quieter than other locations, it provides a chance to connect with nature and enjoy the slower pace of island life. It’s an excellent choice for travellers looking for a tranquil escape while still being close to the vibrant attractions of Lesvos.
Things to do in Mytilene
Mytilene offers a delightful blend of stunning beaches and lush mountains, perfect for hiking and relaxation. Explore ancient ruins and monuments that whisper tales of the past, while the vibrant local atmosphere invites you to savour delicious cuisine. With charming parks and serene lakes, it’s an inviting escape for all.
- Molyvos CastleOpens in a new window – Venture up to Molyvos Castle, a stunning fortress that boasts remarkable views of the surrounding landscape. Explore its ancient walls and imagine the historical events that unfolded here. It's a perfect spot for photography enthusiasts and history lovers alike.
- MólyvosOpens in a new window – Spend some time at Mólyvos, a picturesque beach where you can relax on golden sands or take a refreshing dip in the crystal-clear waters. The charming seaside village offers quaint shops and delightful eateries, making it an ideal spot for a leisurely afternoon.
- Eftalou Hot SpringsOpens in a new window – Unwind at the Eftalou Hot Springs, where natural thermal waters provide a soothing experience. Enjoy the therapeutic benefits while surrounded by beautiful scenery, and don't forget to bring your swimsuit for a dip in the warm pools.
- Monastery of Saint RaphaelOpens in a new window – Visit the Monastery of Saint Raphael, a serene place of worship with stunning architecture. Take a moment to appreciate the intricate details and peaceful atmosphere, perfect for reflection and quiet contemplation.
- Mytilini CastleOpens in a new window – Explore Mytilini Castle, a historic fort that offers insight into the island's rich past. Wander through its expansive grounds, admire the impressive structures, and enjoy panoramic views of Mytilene and the Aegean Sea.
4 tips for savvy savings when booking a hotel in Mytilene
- Book for the cheapest times: The most affordable time to visit Mytilene is during February, November, and December when hotel prices tend to be lower. For those on a budget, a stay of at least 4 to 5 days is recommended to fully appreciate the city’s significant landmarks and cultural gems. During your visit, you can explore historical sites such as museums, the impressive castle, ancient ruins, charming churches, and the captivating marina by the sea. With great value for money, you’ll find that Mytilene offers a rich tapestry of history and architecture, making it a perfect destination for cultural enthusiasts.
- Look for last-minute deals on Hotels.com: To discover last-minute deals for accommodation in Mytilene, begin by exploring the Deals or Last-Minute Deals sections on Hotels.com, where you may find discounted rates on hotels as your travel date approaches. Additionally, consider activating email alerts or push notifications from Hotels.com to stay informed about flash sales and special last-minute promotions, ensuring you don’t miss potential savings. The Smart Shopping tool, available via the app, allows you to compare hotel prices and amenities, helping you make informed choices. You'll be notified if room availability changes or prices drop, increasing your chances of securing a great deal.
- Be flexible with dates: Prices can fluctuate depending on factors such as the hotel's location, star rating, and the time of year. Therefore, being flexible with your travel dates could help you save on your stay at a hotel in Mytilene. For those seeking a distinctive experience, boutique hotels often provide a more personalised touch and may offer better value. When you book through Hotels.com, we will inform you if the price for your chosen dates is above or below the average. If the price appears to be on the higher side, we’ll suggest alternative dates that may be more affordable, increasing the likelihood that you’ll secure a better deal.
- Consider your location: Opting to stay near key attractions or city centres may provide convenience, but it often comes with higher expenses. For more budget-friendly options, consider hotels in less central areas or neighbourhoods, striking a balance between cost and accessibility to the sites you wish to visit. You might also look into independent hotels situated further afield, which are usually more likely to be affordable and can offer a more authentic experience.
Best time to go to Mytilene
Mytilene experiences its lowest average temperature in January, at 49.3°F (9.6°C), while August is the hottest month, with an average temperature of 80.1°F (26.7°C). January is usually the wettest month. June to August are the peak travel months in Mytilene, attracting a higher number of tourists. During this peak period, the weather is sunny, accompanied by no rainfall. On the other hand, January, February, and December tend to be quieter times to visit, marked by light rainfall and mostly sunny conditions.
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